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Ibuprofen
EMT Pharm Review
Term | Definition |
---|---|
trade name | Advil, Motrin |
medication class | Non-steroidal anti-inflammatory drug (NSAID) |
Pharmacologic action | Inhibits synthesis of prostaglandins in body tissues |
indications for administration | For the acute management of pain in patients older than 6 months of age For the acute management of fever in patients older than 6 months of age |
contraindications | Perioperative pain in setting of coronary artery bypass graft (CABG) surgery Preterm infants with suspected or diagnosed, untreated infection Active intracranial or GI bleeding |
contraindications | Thrombocytopenia Coagulation defects Proven necrotizing enterocolitis Significant renal impairment |
Medication interactions | Coumadin Plavix ASA Other NSAIDs or anticoagulants |
adult and pediatric doses | Adult: PO: 10mg/kg up to 800mg Pediatrics: PO: 10mg/kg, not to exceed 800 mg. |
special notes | Febrile seizures occur in normal children between 6 months and 6 years. Such seizures are usually short, lasting less than 5 minutes, generalized, and usually do not require anti-seizure medication therapy. |
special notes | Oncology patients should not receive Ibuprofen or other NSAIDS due to the risk of increased bleeding associated with these medications. |
special notes | Fever may be the result of a toxic ingestion such as Benadryl and other anticholinergics. Risk of toxic ingestion should be considered in all febrile pediatric patients. |
special notes | Ibuprofen is not to be utilized to facilitate treat and release situations. Administration should only be performed if transport is initiated. |