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Acetaminophen (APAP)
EMT Pharm Review
Term | Definition |
---|---|
trade name | Tylenol |
medication class | Antipyretic |
Pharmacologic Action | Reduces fever by reestablishing hemostasis in the hypothalamic heat-regulating center. |
indications for administration | Reduction of fever in pediatric patients to prevent febrile seizures |
contraindications | Hepatic impairment or failure |
Medication interactions | Phenothiazine’s may produce hypothermia Phenobarbital may increase hepatic toxicity |
adult and pediatric doses | Adult: none Pediatric: 10-15mg/Kg PO with a max 24-hour dose of 50mg/kg |
Special Notes | Be aware that multiple OTC and scheduled (pain meds) medications contain acetaminophen, use caution to avoid accidental OD of the patient. An OD greater than 4gm is hepatotoxic |