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Anti-Infective 2

3 anti infective medications for pharm

TermDefinition
Fluconazole of 5 different classes, an anti fungal used for secondary infections caused by other antibiotics.
Fluconazole Uses Candidasis and Histoplasmosis (infection caused by breathing in fungus)
Fluconazole Teachings Take as directed and suspension refrigerate
Fluconazole Nursing Actions Monitor renal/Hepatic function, PT/INR
Fluconazole Side Effects GI upset,
Fluconazole Adverse Reactions TEN, Hepatotoxicity (liver damage)
Fluconazole Interactions Caffeine
Hydroxychloroquine is an Antimalarial
Malaria -travel bug The most prevalent protozoan disease; carried by mosquitoes and has become resistant to treatment
Hydroxychloroquine Uses Malaria and Malaria prophylaxis
Hydroxychloroquine Teachings Routine eye exams. Take on an empty stomach. BEHAVIORAL DISTURBANCES
Hydroxychloroquine Nursing Actions Monitor EKG and Liver function test. and suicidal ideations (Hold and have an evaluation)
Hydroxychloroquine Side Effects Pruritis
Hydroxychloroquine Adverse Reactions Arrythmias, TEN
Hydroxychloroquine interactions Digoxin, neuromuscular blockers
Hydroxychloroquine Contraindications Cardiac disease and Ocular disease, psoriasis
Metronidazole a nitromidazole that disrupts DNA synthesis in susceptible bacteria and protozoa
Metronidazole Uses C. Diff. Trichinosis. BV. Acne Rosacea. Surgical Prophylaxis
Metronidazole Teachings Metallic Taste. Take with food or milk.
Metronidazole Nursing Actions Monitor Weakness. Intake and Output
Metronidazole Side Effects Dry Mouth. Urine Discoloration
Metronidazole Adverse Reactions SJS. TEN.
Metronidazole Interactions Milk thistle
Metronidazole Contraindications Pregnancy. Breastfeeding. Alcohol (DLR)
Adult Immunizations Tetanus, MMR, Varicella, Pneumococcal, Hep A, Hep B, Seasonal FLU, Meningococcal, Herpes Zoster
T dap 10 years and up booster
D Tap Less than 10 years
MMR Live Vaccine. Can't give to pregnant women. Ask for pregnancy test
Varicella Live Vaccine. Can't give to pregnant women. Ask for pregnancy test
Things to know when giving a vaccine pg. 401 Date. Route. Site. Type of vaccine. Manufacturers. Lot #. Expiration. Location of clinic. Name and title of person giving the vaccine.
Mild Reaction Low grade fever. Swelling at the injection site.
Immunization Contraindications Moderate-severe acute illness. History of anaphylaxis. History of reaction to vaccine or vaccine component. Immunocompromised
Tetanus is adm. IM
MMR is adm. SC
Pneumococcal is adm. IM, SC
Varicella is adm. SC
Hep A is adm. IM
Hep B is adm. IM
Influenza is adm. IM, ID, IN
Meningococcal is adm. SC, IM
Herpes Zoster is adm. SC
Fluconazole can cause Hypokalemia
Early signs of Hypokalemia Fatigue. Muscle weakness. Anorexia. Nausea. Vomiting.
Severe S&S of hypokalemia Paresthesia. Leg Cramps. Decreased Bowel Motility. Confusion. Rhabdomyolysis
Signs and Symptoms of Malaria Abdominal cramps. Pruritis. Visual Changes. Dizziness. NVD.
3 types of immunity Active. Passive. Community
Active Immunity Exposed than antigen/pathogen. Body develops antibodies. Occurs naturally (exposure) or actively (vaccine. Slowly and lasts longer
Passive Immunity The body can not form a response, so immunity is passed from antibodies (inactivated vaccines)
Community Immunity (Heard Immunity) Most of the community is immunized which protects the unimmunized (COVID for ex.)
Types of Vaccines Inactive. Attenuated. Toxoids. Conjugate. Recombinant sub-unit. Adjuvant. mRNA
Inactive Killed microorganism
Attenuated Live, weakened microorganisms. Immunocompromised patients shouldn't get these
Toxoids Inactivated toxins can no longer produce harm but do stimulate formation of anti-toxins (tetanus)
Conjugate New vaccine that require a protein or toxoid from another organism to link to produce an immune response. (h.flu B for infants)
Recombinant sub-unit include some genetic material (DNA) of a pathogen which stimulates antibody production. These antibodies are then used as the vaccine (hep B)
Adjuvant Added to a vaccine to improve the bodies response. Usually aluminum salts.
mRNA Vaccines are now being used. These teach the cell to make a protein that triggers an immune response, similar to conjugate or sub-unit. These are quicker to produce because the others require a human protein.
Where is IM given? Deltoid for adults (shoulder)
Where is Sub Q (SC) given? In either the outer aspect of the upper arm or anterolateral thigh. (NO ABDOMEN)
Created by: Felicitylee92
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