click below
click below
Normal Size Small Size show me how
Endocrine 1
Generic | Brand | Pharmacologic Category | Common Indications | Essential Knowledge |
---|---|---|---|---|
metformin (PO) | Glucophage, Glucophage XR | Biguanide | Type 2 DM, PCOS (polycystic ovarian syndrome) | KSE: diarrhea, nausea, vomiting USBW: lactic acidosis |
sitagliptin (PO) | Januvia | Dipeptidyl peptidase (DPP-4) inhibitor | Type 2 DM | Key side effects: headache, nausopharyngitis |
empagliflozin (PO) | Jardiance | Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | Type 2 DM, HF | Key side effects: UTI |
glimepiride (PO) | Amaryl | Sulfonylurea | Type 2 DM | Key side effects: hypoglycemia, weight gain |
glipizide (PO) | Glucotrol, Glucotrol XL | Sulfonylurea | Type 2 DM | Key side effects: hypoglycemia, weight gain |
glyburide (PO) | Glynase | Sulfonylurea | Type 2 DM | Key side effects: hypoglycemia, weight gain |
pioglitazone (PO) | Actos | Thiazolidinedione (TZD) | Type 2 DM | KSE: edema, weight gain, upper respiratory tract infection USBW: may exacerbate congestive heart failure and CI in NYHA Class III and IV |
liraglutide (SQ) | Victoza, Saxenda | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM, chronic weight management | Key side effects: nausea, vomiting, diarrhea, constipation USBW: may increase risk of thyroid c-cell tumor |
insulin detemir (SQ) | Levemir | Insulin, long acting | Type 1 DM, type 2 DM | Key side effects: hypoglycemia, weight gain |
insulin glargine (SQ) | Lantus, Toujeo, Basaglar | Insulin, long acting | Type 1 DM, type 2 DM | Key side effects: hypoglycemia, weight gain |
insulin NPH (SQ) | Humulin N, Novolin N | Insulin, intermediate acting | Type 1 DM, type 2 DM | Key side effects: hypoglycemia, weight gain |
insulin aspart (SQ) | Novolog | Insulin, rapid acting | Type 1 DM, type 2 DM | Key side effects: hypoglycemia, weight gain |
insulin lispro (SQ) | Humalog | Insulin, rapid acting | Type 1 DM, type 2 DM | Key side effects: hypoglycemia, weight gain |
insulin regular (SQ, IV) | Humulin R, Novolin R | Insulin, short-acting | Type 1 DM, type 2 DM, DKA | Key side effects: hypoglycemia, weight gain |
levothyroxine (PO, IV) | Synthroid, Levoxyl | Thyroid product | Hypothyroidism | Key side effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance USBW: not intended for use for weight loss ON: narrow therapeutic index drug (therapeutic monitoring is recommended) not all generic products are therapeutically equiv. |
thyroid, dessicated (PO) | Armour Thyroid | Thyroid product | Hypothyroidism | Key side effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance USBW: not intended for use for weight loss ON: narrow therapeutic index drug (therapeutic monitoring is recommended) not all generic products are therapeutically equiv. |
sitagliptin and metformin (PO) | Janumet, Janumet XR |