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Pain Heme, Onc 1
Generic | Brand | Category | Indication | Side Effects |
---|---|---|---|---|
fentanyl (transdermal, IV) | Transdermal: Duragesic, IV: Sublimaze | Opioid analgesic | Pain | dizziness, drowsiness, itching, nausea, vomiting, constiptn, respitory deprssn (dose) BW:addictn, abuse, misuse, fatal resp. deprsn, accidntl ingestn ->fatal OD; neonat w/drwl syndme; inducd w/drwl; w/ benzos/CNS deprsnts, profnd sedatn,coma, death |
hydromorphone (PO, IV) | Dilaudid | Opioid analgesic | Pain | dizziness, drowsiness, itching, nausea, vomiting, constiptn, respitory deprssn (dose) BW:addictn, abuse, misuse, fatal resp. deprsn, accidntl ingestn ->fatal OD; neonat w/drwl syndme; inducd w/drwl; w/ benzos/CNS deprsnts, profnd sedatn,coma, death |
morphine (extended release) (PO) | MS Contin, Kadian | Opioid analgesic | Pain | dizziness, drowsiness, itching, nausea, vomiting, constiptn, respitory deprssn (dose) BW:addictn, abuse, misuse, fatal resp. deprsn, accidntl ingestn ->fatal OD; neonat w/drwl syndme; inducd w/drwl; w/ benzos/CNS deprsnts, profnd sedatn,coma, death |
morphine (immediate release) (PO, IV, IM, PR) | IV: Duramorph | Opioid analgesic | Pain | dizziness, drowsiness, itching, nausea, vomiting, constiptn, respitory deprssn (dose) BW:addictn, abuse, misuse, fatal resp. deprsn, accidntl ingestn ->fatal OD; neonat w/drwl syndme; inducd w/drwl; w/ benzos/CNS deprsnts, profnd sedatn,coma, death |
oxycodone (PO) | Oxycontin, Roxicodone | Opioid analgesic | Pain | dizziness, drowsiness, itching, nausea, vomiting, constiptn, respitory deprssn (dose) BW:addictn, abuse, misuse, fatal resp. deprsn, accidntl ingestn ->fatal OD; neonat w/drwl syndme; inducd w/drwl; w/ benzos/CNS deprsnts, profnd sedatn,coma, death |
methadone (PO, IV) | Dolophine | Opioid analgesic | Opioid use disorder, severe chronic pain | dizziness, drowsiness, nausea, vomiting, constipation, respiratory depression (dose-related), QTc prolongation US Boxed Warnings QTc interval prolongation and serious arrhythmia (Torsades de Pointes) have occurred during treatment |
acetaminophen (PO, PR, IV) * | PO/PR: Tylenol, IV: Ofirmev | Analgesic (non-opioid), antipyretic | Pain, fever | nausea, vomiting, increased hepatic transaminases US Boxed Warnings: total daily dose from all sources should not exceed maximum daily limit; hepatotoxicity |
tramadol (PO) | Ultram, Ultram ER | Central analgesic; partial opioid agonist | Pain | dizziness, drowsiness, nausea, vomiting, constipation, respiratory depression (dose-related) US Boxed Warnings: serious or fatal respiratory depression may occur Other Notes: lowers seizure threshold |
hydrocodone and acetaminophen (PO) | Lortab, Vicodin, Norco | Opioid and nonopioid analgesic combination | Pain | dizziness, drowsiness, nausea, vomiting, constipation, respiratory depression (dose-related) |
oxycodone and acetaminophen (PO) | Percocet, Endocet, Roxicet | Opioid and nonopioid analgesic combination | Pain | dizziness, drowsiness, nausea, vomiting, constipation, respiratory depression (dose-related) |
codeine and acetaminophen (PO) | Tylenol with Codeine #3, Tylenol with Codeine #4 | Opioid and nonopioid analgesic combination | Pain | dizziness, drowsiness, nausea, vomiting, constipation, respiratory depression (dose-related) |
naloxone (IV, IM, SQ, intranasal) | Narcan | Opioid antagonist | Opioid overdose | headache, opioid withdrawal syndrome in opioid-dependent populations, pain, diaphoresis ON: potentially life-threatening respiratory depression (when w/ CNS and respitry depresnts); reduces poss. of parenteral misuse by opioid withdrawal when injected |
buprenorphine and naloxone (SL) | Suboxone | Partial opioid agonist and opioid antagonist | Opioid use disorder | headache, opioid withdrawal syndrome in opioid-dependent populations, pain, diaphoresis ON: potentially life-threatening respiratory depression (when w/ CNS and respitry depresnts); reduces poss. of parenteral misuse by opioid withdrawal when injected |