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Endocrine 1
Generic | Brand | Category | Indication | Side effects |
---|---|---|---|---|
metformin (PO) | Glucophage, Glucophage XR | Biguanide | Type 2 DM, PCOS | diarrhea, nausea, vomiting US Boxed Warnings: lactic acidosis |
sitagliptin (PO) | Januvia | Dipeptidyl peptidase (DPP-4) inhibitor | Type 2 DM | headache, nasopharyngitis |
empagliflozin (PO) | Jardiance | Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | Type 2 DM, HF | UTI |
glimepiride (PO) | Amaryl | Sulfonylurea | Type 2 DM | hypoglycemia, weight gain |
glipizide (PO) | Glucotrol, Glucotrol XL | Sulfonylurea | Type 2 DM | hypoglycemia, weight gain |
glyburide (PO) | Glynase | Sulfonylurea | Type 2 DM | hypoglycemia, weight gain |
pioglitazone (PO) | Actos | Thiazolidinedione (TZD) | Type 2 DM | edema, weight gain, upper respiratory tract infection US Boxed Warnings: may exacerbate congestive heart failure and CI in NYHA Class III and IV |
liraglutide (SQ) | Victoza, Saxenda | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM, chronic weight management | nausea, vomiting, diarrhea, constipation US Boxed Warnings: may increase risk of thyroid c-cell tumor |
insulin detemir (SQ) | Levemir | Insulin, long acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain |
insulin glargine (SQ) | Lantus, Toujeo, Basaglar | Insulin, long acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain |
insulin NPH (SQ) | Humulin N, Novolin N | Insulin, intermediate acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain |
insulin aspart (SQ) | Novolog | Insulin, rapid acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain |
insulin lispro (SQ) | Humalog | Insulin, rapid acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain |
insulin regular (SQ, IV) | Humulin R, Novolin R | Insulin, short-acting | Type 1 DM, type 2 DM, DKA | hypoglycemia, weight gain |
levothyroxine (PO, IV) | Synthroid, Levoxyl | Thyroid product | Hypothyroidism | weight loss, palpitations, diarrhea, insomnia, heat intolerance US BW: not intended for use for weight loss Other Notes: narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent |
thyroid, dessicated (PO) | Armour Thyroid | Thyroid product | Hypothyroidism | weight loss, palpitations, diarrhea, insomnia, heat intolerance US BW: not intended for use for weight loss Other Notes: narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent |
sitagliptin and metformin (PO) | Janumet, Janumet XR | Biguanide and Dipeptidyl peptidase (DPP-4) inhibitor | Type 2 DM, PCOS | headache, nasopharyngitis, diarrhea, nausea, vomiting US Boxed Warnings: lactic acidosis |