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serology
MT
| Question | Answer |
|---|---|
| Fimbriae | Structures that arise near the plasma membrane and project through the cell wall |
| Protein found in association with the hyluronic capsule | M-Protein |
| Streptolysin O (SLO) | Oxygen liable enzyme, binds to sterols in the red blood cell membrane |
| Oxygen-stable enzyme is responsible for beta hemolysis on a blood agar plate | Streptoysin S |
| Spreading factor,braks down hyaluronic acid found in host tissue | Hyaluronidase |
| Streptokinase | an enzyme that dissolves clots by turning plasminogen to plasma |
| elaborated by scarlet fever and shows a rash | Erythrogenic Toxin |
| S.Pyogenes | Causes infections in upper respiratory system and strep throat |
| ASO and Anti-DNase B | Are used for titers for S pyogenes |
| Superantigens | Are capable of binding to alpha/beta T-cell receptors |
| S. Agalactiae | Serious disease in adults and neonates |
| Syphilis is caused by | Spirochete |
| What is transmitted by sexual contact in humans | Treponema Pallidum |
| What happens to progressions of untreated syphillis | divided into stages |
| Classic serologic test for syphillis measure the antibody--2 types | Treponemal-nontreponemal |
| Lyme disease | caused by a spirochete bacterium or a hard body tick called Borrelia burgdorferi |
| Unique exspanding skin lesion,tick bite to human skin | (EM) Erythema migrans |
| What does Lyme borreliosis affects, what type of body parts | Skin,nervous system,heart and joints |
| Most common labboratory assays for B.Burgdorferi for antibody detection are | IFA,ELISA,PreVue |
| OspA and OspB are proteins from bacterial outer wall from what | B Burgdorferi |
| Ehrlichiosis | general term for both anaplasmosis and HME |
| Possibly a fatal tick borne disease | Babesia |
| A mosquito-borne virus present in the US | West nile Virus |
| West nile Virus is detected by | RT-PCR |
| Birds and mamals, undercooked raw meat | Toxoplasma gondi |
| Definite host of toxoplasma gondi | House cat |
| What test is used for the detection of T.Gondi | ELISA |
| CMV---Cytomegalovirus | member of the herpes virus |
| Most common virus transmitted to the fetus | CMV |
| CID | may be fatal, can cause permanent neurologic sequelae |
| CMV can be transferred in 2 ways | Transfussion of fresh blood or organ transplant |
| CMV is a major cause of | congenenital viral infections |
| A human herpesvirus | EBV |
| This virus causes complications such as cardiac,ocular,respiratory,hematologic,digestive,renal, and neurologic systems. | EBV |
| The guinea pig kidney contains what type of antigen | Forssman antigen |
| What is the cause of monnucleosis | EBV virus |
| The EBV can be a major concern for what type of individuals | Immunocompromised patients |
| What antibodies are present in infectious mononucleosis | Heterophil and EBV antibodies |
| Inflammation of the liver is | Hepatitis |
| Four phases of acute hepatitis | Incubation,preicteric,icteric and convalescence |
| If a patient is HBsAg and Anti-HBc positive, this means | Chronically infected |
| Pharyngitis,Scarlet fever, and Impetigo are causes from what | S.Pyogenes |
| Hyaluronidase | Also called spreading factor |
| Dissolves clots by converting plasminogen into plasma | Streptokinase |
| Responnsible for characteristics scarlet fever rash | Erythrogenic toxin |
| S.pyogenes is usually | Beta hemolytic |
| Provides specific immunity,inhibits phagocytosis and found w/hyaluronic capsule | M-protein |
| hyalurondase,D-nase and Erythrogenic toxin is produced by what | S.pyogenes |
| Presence of betalipoprotein,bac contamination and shaking of a reagent causes | False ASO reults |
| Long term complications of S.pyogenes are from | R.fever and poststrep |
| Proteolytic enzymes causes | Necrotizing fasciitis |
| Highest reported levels of sensitivity testing for Gr.A strep are | Surface/optical immunassay |
| Diagnosis of strep and ASO cannot be used,whats next | Anti -D-NAse-B |
| Hutchinson teeth is called | Congenital syphilis |
| Syphillis is to | Trep. Pallidium |
| Bejel is to | T.Pallidum |
| Nontreponal antibodies produce by a infected person is caleed | Reagin antibodies |
| FTA-ABS test and MHA-TP test are | Treponemal method |
| Nontreponemal method | RPR test |
| Infectious.Monoucleosis,leprosy and R.arthritis can cause a false pos on what test | RPR procedure |
| Treponema pallidium blood in 4C last how long | 3 days |
| How long is the incubation period for Syphillis | 3 weeks |
| The serologic method of syphillis is called what phase | Latent phase |
| Ixodes pacificus,I.scapularis and I.ricinus creats what | Lyme disease |
| What test is used to distinquish between true pos and false pos | PCR-Polymerse chain reaction |
| Symptoms of lyme meningitis is | Severe headache and siff neck. |
| Retinal detachment,loss of vision and cranial nerve palsies are caused by | Lyme disease |
| Flagellar 41 KD polypeptide is fisrt reponse from what antigen | B.Burgdorferi |
| Ehrlichia species are also known for | Rocky mountain spotted fever |
| Babesiosis is caused by | Babesia microti |
| Where can you find Babesiosis organism in the body | Peripheral blood |
| Parasitic infection is caused by | Toxoplasmosis |
| The host for T-gondii is | Domestic cat |
| What descibes CMV | Herpes, DNA virus and cell associated virus |
| Cell associated viruses is similar to | herpesvirus |
| What common way would you attract the CMV virus | Venereal route |
| VCA means | Viral CApsid antigen |
| EBV can cause what diseases | monoucleosis,lymphoma and carcinoma |
| What is the mode of transmission of EBV | Oral secretions |
| B-type,capsid antigen and early antigen are characteristics of | EBV infected lymphocytes |
| Infectious monoucleosis has no | acute stage |
| Paul bunnell screening test uses | sheep erthrocytes |
| Davidson diff test screening test uses | beef erythrocytes |
| Monoslide agglutination test uses | horse erythrocytes |
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