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Drug List

Top 200 Drugs: Drug List One #120-140

GenericBrandIFUClassificationMOAADR & Black Box
Cholecalciferol Vitamin D3 Vitamin D Deficiency Vitamin D Supplement Bind to vitamin D receptor (VDR) sites found throughout the body. • Aids with uptake and utilization of Ca+ • Maintenance of bones and calcium/phosphorus homeostasis • Protective effects from several diseases like HTN, DM, CA, cardiovascu ADR: CNS, CV
Ramipril Altace Hypertension ACE Inhibitors An angiotensin converting enzyme (ACE) inhibitor used for treating high blood pressure, heart failure and for preventing kidney failure due to high blood pressure and diabetes. • ACE is an enzyme responsible for producing the chemical, angi ADR: CV, Respiratory Black Box: Fetal Toxicity
Nifedipine Procardia Hypertension Ca+ Channel Blocker • Antiarrhythmic that dilates arteries and decreases heart rate = lower blood pressure and decreases work load of the heart. ADR: CNS, CV
Drospirenone/ Ethinyl Estradiol Ocella Birth Control Oral Contraceptive A combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary) and potential fertilization. • Changes cervical mucus and uterine lining, making it harder for sperm to reach the uteru ADR: CNS, GI Black Box: Cigarette Smoking
Valsartan Diovan Hypertension Angiotensin Receptor Blocker (ARB) ARBs block angiotensin II from attaching to receptor sites and causing vasoconstriction which increases BP ADR: Renal Black Box: Fetal Toxicity
Pioglitazone HCL Actos Type II Diabetes Oral Hypoglycemic (Thiazolidinedione or “Glitazones”) Lowers blood glucose by improving target cell response to insulin, without increasing pancreatic insulin secretion. • It’s mechanism of action is dependent on the presence of insulin in order to work. ADR: CV, Endocrine Black Box: Congestive Heart Failure
Famotidine Pepcid GERD H2-Receptor Antagonist Prevents Histamine from binding to H2 receptor sites in the stomach, which inhibits gastric acid secretion ADR: CNS, GI
Methylprednisolone Medrol Inflammation Glucocorticoid Decreases inflammation by suppressing of movement of leukocytes and reversing capillary permeability. ADR: Endocrine, CNS
Clindamycin Cleocin Bacterial Infection Antibiotic • Prevents protein synthesis needed by bacteria for survival. • Decreases bacterial growth and kills invasive bacterial that is present. ADR: CV, Dermatologic Black Box: Colitis
Risperidone Risperdal Bipolar D/O, Schizophrenia Agitation assoc. w/ Autism Second Generation Antipsychotic (SGA) Rebalances neurotransmitters dopamine and serotonin to improve thinking, mood, and behavior. ADR: CNS, GI Black Box: Increased mortality in elderly
Rivaroxaban Xarelto Coronary Artery Disease, Thrombus, Embolus Anticoagulant Inhibits platelet activation and clot formation by inhibiting clotting factor Xa (FXa) in two coagulation pathways. • By stopping clotting factor Xa the blood becomes thinner and takes longer to clot ADR: Hematologic, CNS Black Box: Thrombotic Events
Hydroxychloroquine Sulfate Plaquenil Malaria, Lupus, Rheumatoid Arthritis Disease-Modifying Anti-Rheumatic Drug (DMARD) Regulates the activity of the immune system and prevents it from overacting in some conditions (RA, Lupus) • Can alter the underlying disease rather than simply treating the symptoms by interacting with the DNA of the microorganism and inhi ADR: CNS, Dermatologic
Aripiprazole Abilify GERD Proton Pump Inhibitor (PPI) The enzyme HydrogenPotassium ATPase present in the stomach maintains the acidity of gastric secretions. • PPIs block the enzyme Hydrogen-Potassium ATPase thereby reducing stomach acidity. ADR: CNS, Endocrine Black Box: Increased mortality in elderly
Mometasone Elocon Allergic Rhinitis Corticosteroid Reduces inflammation in the nasal passages caused by seasonal/ environmental allergens by decreasing leukotriene production and tissue permeability. ADR: CNS, GI
Sumatriptan Imitrex Migraine Headaches Antimigraine Agent Causes vasoconstriction of intracranial blood vessels • Reduces neurogenic inflammation associated migraines ADR: CNS
Dextroamphetamine ProCentra Attention-Deficit/ Hyperactivity Disorder (ADHD), Narcoleps CNS Stimulant Promote release of neurotransmitters dopamine and norepinephrine from nerve terminals and blocks their reuptake leaving more of the chemicals available for chemical reactions and signal transmission. ADR: CV, CNS Black Box: High Abuse Potential
Lansoprazole Prevacid GERD Proton Pump Inhibitor (PPI) The enzyme HydrogenPotassium ATPase present in the stomach maintains the acidity of gastric secretions. • PPIs block the enzyme Hydrogen-Potassium ATPase thereby reducing stomach acidity. ADR: CNS, GI
Baclofen Gablofen Myospasms Muscle Relaxant • Inhibits the transmission of reflexes at the spinal cord level resulting in relief of muscle spasticity ADR: CNS, GI Black Box: Abrupt Withdrawal
Mirtazapine Remeron Depression Tetracyclic Antidepressant (TCA) Increases the release of neurotransmitters norepinephrine and serotonin. More of these chemicals available in the brain helps to improve mood and stabilize emotions. • It does not inhibit the reuptake of norepinephrine or serotonin. ADR: CNS, GI Black Box: Suicidal Thoughts
Promethazine Phenergan Nausea, Vomiting Antiemetic & Antihistamine (H1 Antagonist) • Blocks receptors in your brain that can cause nausea and vomiting • Competes with histamine for histamine (H1) receptor sites • Decreases stimuli sent from the GI tract to the brain stem ADR: CV, Otic Black Box: Respiratory Depression
Created by: aaishat
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