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1.11
Uterine Cycle/Menstrual Cycle
Term | Definition |
---|---|
Three phases of menstrual cycle | 1. follicular phase (preovulatory) 2. ovulation phase (mid-cycle) 3. luteal phase (postovulatory) |
when does the menstrual cycle being? | when estrogen and progesterone levels have fallen |
the uterine endometrial functional zone cannot be sustained in absence of __________ and begins to shed (menses). This is considered to be day _______. | progesterone day 0 |
What responds to falling estrogen and progesterone at the end of the uterine cycle? | Pituitary |
the pituitary increases _______ and _________ secretion | LH and FSH |
What does FSH do? | recruits several follicles and stimulates them to enter rapid growth phase |
______ and ______ together inhibit FSH secretion by a negative feed back inhibition. | estrogen and inhibin |
proliferation of endometrium is stimulated by ______ | estrogen |
Declining FSH levels progressively causes _______ of all but one follicle | atresia (degradation) |
Secretion of all but one follicle leads to selection of a _________, which produces high levels of ______. | dominant follicle, estrogen |
high levels of _______has a positive feedback (not inhibitory) effect on the gonadotropes, causing a _______ | estrogen, LH surge (some FSH surge) |
proliferation of ________by estrogen continues | endometrium |
LH surge induces __________ of the dominant follicle | maturation |
LH surge induces: | ovulation and luteinization |
Corpus luteum produces: | high progesterone, low levels estrogen and inhibin |
what causes feedback inhibition of LH and FSH, which brings them back to normal? | high progesterone, estrogen and inhibin |
high progesterone levels shifts ______ into ______ phase | endometrium into secretary phase |
high progesterone levels inhibits: | further endometrial growth by down regulating estrogen receptors (ER) |
Corpus Luteum progressively becomes less sensitive to: | basal LH |
Corpus Luteum dies if the _____ levels do not increase (fertilization of the egg) | hCG |
Corpus Luteum dies if the ______sheds (low progesterone) and cycle beings again. | endometrium |