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Endocrine 2
BDK
generic | brand | pharmacological category | common indication | essential knowledge |
---|---|---|---|---|
drospirenone and ethinyl estradiol (PO) | Yasmin, Yaz | contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
levonorgestrel and ethinyl estradiol (PO) | Lutera, Levora, Seasonique | contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
norethindrone and ethinyl estradiol (po) | Junel, Loestrin , Microgestin | Contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
norethindrone, ethinyl estradiol, and ferrous fumarate (PO) | Lo loestrin Fe, Microgestin Fe | contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
norgestimate and ethinyl estradiol (PO) | Ortho Tri-cyclen Lo, Tri-Sprintec, Sprintec | contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
norgestrel and ethinyl estradiol (PO) | Crysell-28, Low-Ogestrel | contraceptive | contraception, acne | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic |
estrogens, conjugated (equine) (PO, topical) | Premarin | Estrogen derivative | vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: irritation at application site (transdermal patch only), abdominal pain, breast tenderness, thromboembolic disorders (myocardial infarction, stroke, VTE) US Boxed Warnings: increased risk of breast cancer; should not be used for dementi |
estradiol (transdermal, PO) | Transdermal: Vivelle dot PO: Estrace | Estrogen derivative | vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | Key Side Effects: irritation at application site (transdermal patch only), abdominal pain, breast tenderness, thromboembolic disorders (myocardial infarction, stroke, VTE) US Boxed Warnings: increased risk of breast cancer; should not be used for dementi |
medroxyprogeterone (PO) | Provera | Progestin | Abnormal uterine bleeding, secondary amenorrhea | Key Side Effects: acne, abnormal menstrual bleeding, headache, amenorrhea US Boxed Warnings: increased risk of breast cancer; should not be used for dementia prevention; should not be used for prevention of cardiovascular disease Other Notes: CI in thro |