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chap 12
Question | Answer |
---|---|
drug drug interactions - Increased bleeding risk | warfarin + aspirin |
drug drug interactions - hyperkalemia ( high potassium blood levels) | lisinopril + spironolactone |
drug drug interactions - increased digoxin levels | digoxin + amiodarone or verapamil |
drug drug interactions - increased risk theophylline toxicity | fluroquinolones (ciprofloxacin) + theophylline |
drug drug interactions - increased bleeding risk | warfarin + fluroquinolone or macrolide antibiotic (azithromycin) |
drug drug interactions - increased statin side effect | azole antifungals + statins |
Drug-Dietary supplement interaction- too much serotonin (serotonin syndrome= increased BP, H/A, seizure, etc) | Antidepressants + St.John's wort |
Drug-Dietary supplement interaction- risk of drowsiness | Benzodiazepines (alprazolam) + kava kava |
Drug nutrient interactions - increased clotting decreased efficacy | warfarin + vit k rich food (dark leafy greens) |
Drug nutrient interactions -decreased levels | Tetracyclines + calcium rich foods (milk) |
Drug food interaction - increased BP to dangerously high levels | MAOIs (phenelzine, selegiline) + tyramine (in aged/fermented foods such as wine, cheese, cured meats) |
Drug food interaction - increased statin levels increased side effects | atorvastatin + grapefruit |
drugs that interact with grape fruit | alprazolam, amiodarone, carbamazepine , e-mycin, clarithromycin, felodipine, verapamil, warfarin, colchicine cyclosporine, |
Drug disease interaction - can worsen asthma | Betablockers (propanolol) |
Drug disease interaction - can increase BP to dangerously high levels in patients with increased BP | Nasal decongestants (pseudoephedrine) |
Drug disease interaction - can worsen peptic ulcer disease | aspirin/ NSAIDs |
Drug disease interaction - worsen CHF | NSAIDs - fluid retention |
Drug disease interaction - increased blood sugar levels , worsen diabetes control | steriods (prednisone) |
Drug Laboratory Interactions - increases thyroid levels | Levothroxine |
Drug Laboratory Interactions - can alter urine glucose and ketone tests | Cephalosporin Antibiotics |