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Antianginal

Cardio

QuestionAnswer
nitrates/nitrites nitroglycerin, nitrol, isorbide dinitrate
beta-blockers atenolol, metoprolol
calcium channel blockers diltiazem, nifedipine, verapamil
nitrates/nitrites relax smooth muscles surrounding blood vessels leading to dilation; potent dilating effect on coronary arteries
beta-blockers bind to and block beta-adrenergic receptors causing slowing of HR and decreased contractility; decrease workload of heart
calcium channel blockers depress automaticity of and conduction through SA and Av nodes decreasing cardiac contractility and decreasing peripheral and coronary artery tone; verapamil and diltiazem decrease heart rate
nitrates/nitrites adverse effects dizziness, H/A, hypotension, tachycardia, syncope, flushing, withdrawal, sublingual burning
beta-blocker adverse effects AV block, CHF, bradycardia, hypoglycemia, fatigue, depression, sexual dysfunction
calcium channel blocker adverse effects increased urinary frequency, incontinence, bradycardia, AV block, CHF
nitrate/nitrite desired effects relief or prevention of anginal attacks, increased cardiac output, reduction of BP
beta- blocker desired effects decreased BP and HR; decreased frequency of angina pectoris; decreased rate of cardiovascular mortality and hospitalization in pts with heart failure
calcium channel blocker desired effects systemic vasodilation resulting in decreased BP; coronary vasodilation resulting in decreased frequency and severity of angina; suppression of arrhythmias
Created by: 2a2j
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