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Adrenerg & Cholinerg
Sympathetic / Parasympathetic Nervous System
| Term | Definition |
|---|---|
| Definition of Adrenergic Drugs | Fight or flight / Sympathetic Nervous System ---> stimulate Sympathetic Nerves and send more blood to vital organs needed to fight or run - primarily impact cardiac, circulator, and respiratory systems |
| Adrenergic Drug Actions | - Mimics the Sympathetic Nervous System (all of the actions that would happen during a fight or flight response) |
| Adrenergic Selective Drugs | - Adrenergic nerves have either alpha or beta receptors - Selective: can act on alpha or beta but not both - Nonselective: acts on both alpha and beta (do not have a choice) |
| Adrenergic Receptors (Alpha) | - Alpha 1: vasoconstriction peripheral blood vessels - Alpha 2: presynaptic neuron: regulates release of neurotransmitters and decreases tone, motility, and secretions of GI tract |
| Adrenergic Receptors (Beta) | - Beta 1: myocardium: increased heart rate, increased force of myocardial contraction - Beta 2: vasodilation of peripheral blood vessels and bronchodilation |
| Adrenergic Uses | - Shock - Respiratory distress - Allergic reaction - Heart block - Hypotension |
| Adrenergic Prototypes | - Norepinephrine / Levophed - Dopamine - Epinephrine / Epi pen |
| Definition Adrenergic Blocking Drugs | Block effects of fight or flight response Purpose: block transmission of Norepinephrine |
| Adrenergic Blocking Drug Classes | - Alpha Adrenergic Blocking: Alpha Blockers (causes vasodilation) - Beta Adrenergic Blocking: Beta Blockers (decrease HR, dilate blood vessels) - Alpha/Beta Adrenergic Blocking: Block Alpha and Beta receptors and peripheral vasodilation |
| Alpha Blockers ADRs | - Orthostatic hypotension - Hypotension - Tachycardia - Cardiac arrythmias |
| Alpha Blocker Prototype | Phentolamine |
| Beta Blockers ADRs | - Hypotension - Orthostatic hypotension - Bradycardia - Bronchospasm |
| ***Should you give a Beta Blocker to someone with asthma? | NO |
| Beta Blocker Prototype | Metoprolol / Lopressor |
| Alpha/Beta Blocker ADRs | - Hypotension - Bradycardia - Skin rash - Dyspnea (shortness of breath) |
| Alpha/Beta Blocker Prototype | - Carvedilol / Coreg - Labetalol |
| Cholinergic Pathway | ACETYLCHOLINE |
| Cholinergic Agonist | - Can treat myasthenia gravis (nerve/muscle disorder) - Treats dry mouth, urinary retention, and every now and then glaucoma - Can cause: increased GI motility, increased bladder contractions, increase in saliva/sweating, difficulty breathing in asthma |
| Cholinergic Blocking | - Treats asthma, COPD, urinary retention, gastroparesis, bladder spasm, hyperhydrosis - Can cause: dry mouth, constipation, visual changes, decreased sweating, somnolence - Do not give to someone with heart failure |
| Cholinergic Agonist & Blocking | Can equal eachother out - so you would not take both |
Created by:
alowe26
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