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Antidepressants
MAOIs(Monoamine Oxidase Inhibitors) - Phenelzine
Question | Answer |
---|---|
Expected pharmacological action | inhibit activity of monoamine oxidase resulting in an increase in epi, norepi, dopamine, seratonin, stimulate CNS |
Therapeutic Use | Less frequently used in depressive episodes Used as a last resort OLD AND HIGHLY INTERACTIVE |
Adverse reactions | Severe- hypertensive crisis may happen when foods containing tyramine are eaten can interact with many meds |
Foods with tyramine | processed meats aged cheese soy sauce |
Contraindications | allergy liver/kidney disease cerebrovascular disease hypertension/conjestive heart failure history of headaches |
Precautions | Pregnant (C)/ lactating younger than 16 HX of seizures Diabetes Hyperthyroidism Suicidal ideation/behavior |
Interactions | EVEYRTHING - TYRAMINE |
Can you stop this drug abruptly? | NO, taper for 2-4 weeks |
Client Education | Takes weeks/months to work Watch for behavioral changes drink H20 mood log be careful in sun |