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Anxiolytics

Lorazepam/Ativan (Benzodiazepines)

QuestionAnswer
Expected Pharmacological Action Block neurotransmitter receptor sites by increasing the effects of GABA.
Theraputic Use Acute anxiety Alcohol withdrawal Anti-emitic (stop nauseousness) Behavior issues Seizures
Adverse Reaction Headaches, muscle aches (rigidity) Restlessness and Insomnia Memory Loss, hallucinations, psychosis Metallic Taste Sedation and Dry Mouth
Contraindications Allergy Acute narrow angle glucoma pregnancy (D) - floppy infant syndrome Buspirone - NONBENZO Coma/Shock Acute alcoholic intoxication and low vital signs
Precautions Elderly Poor Liver function impaired renal function debilitation
Interactions alcohol, opioids - risk for CNS depression antipyschotics - risk of sedation and respiratory depression tricyclic antidepressants (very dry mouth) Digoxin - increased digoxin toxin levels (cardiac problems)
Can people be dependent on this drug? YES scheduled IV- habit forming - risk for abuse - develop tolerance Med should be tapered when stopped 1-10mg daily, 4mg IV pre-anesthesia , 1mg most common
What is the benzodiazepine antagonist when there is benzodiazepine toxicity? Flumazenil is the antidote
what does PAM or LAM stand for? ANXIETY MEDS
Client Education Prevent constipation by eating high fiber foods and drinking a lot of fluids Dry mouth - sips of water and suck on hard candy or sugarless gum Rise from bed/chair slowly
Is this a short or a long term drug? Short term!
Created by: Mplaster
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