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Endocrine 3
Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects/Other Notes | Other Notes | US Boxed Warning |
---|---|---|---|---|---|---|
testosterone gel (topical) | AndroGel, Fortesta, Vogelxo | Androgen | Hypogonadism | Key Side Effects: contact dermatitis, acne, increased prostate specific antigen (PSA), emotional lability, hypertension | US Boxed Warning: secondary exposure may result in virilization (especially in children); CI in males with breast or prostate cancer and pregnant women | |
alendronate (PO) | Fosamax | Bisphosphonate | Osteoporosis | Key Side Effects: dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw | Other Notes: CI in patients with abnormalities of the esophagus; administer ≥30 minutes before food or drink (except plain water); remain upright for 30 minutes following dose to reduce esophageal irritation | |
ibandronate (PO, IV) | Boniva | Bisphosphonate | Osteoporosis | Key Side Effects: dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw | Other Notes: (oral only): CI in patients with abnormalities of the esophagus; administer ≥60 minutes before food or drink (except plain water); remain upright for 60 mins following dose to reduce esophageal irritation | |
raloxifene (PO) | Evista | Selective estrogen receptor modulator (SERM) | Osteoporosis, breast cancer prevention | Key Side Effects: hot flashes, leg cramps, peripheral edema, arthralgia | US Boxed Warning: increased risk of thromboembolism; increased risk of death caused by stroke in patients with cardiovascular disease | |
sildenafil (PO) | Viagra, Revatio | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, PAH | Key Side Effects: priapism, headache, flushing, visual disturbance Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) | ||
tadalafil (PO) | Cialis | Phosphodiesterase-5 enzyme (PDE5) inhibitor | ED, BPH | Key Side Effects: priapism, headache, flushing, visual disturbance Other Notes: CI with concomitant use of nitrates (may cause severe hypotension) |