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Endocrine 1
Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects/Other Notes | US Boxed Warning |
---|---|---|---|---|---|
metformin (PO) | Glucophage, Glucophage XR | Biguanide | Type 2 DM, PCOS | Key Side Effects: diarrhea, nausea, vomiting | US Boxed Warning: lactic acidosis |
sitagliptin (PO) | Januvia | Dipeptidyl peptidase (DPP-4) inhibitor | Type 2 DM | Key Side Effects: headache, nasopharyngitis | |
empagliflozin (PO) | Jardiance | Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | Type 2 DM, HF | Key Side Effects: UTI | |
glimepiride (PO) | Amaryl | Sulfonylurea | Type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
glipizide (PO) | Glucotrol, Glucotrol XL | Sulfonylurea | Type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
glyburide (PO) | Glynase | Sulfonylurea | Type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
pioglitazone (PO) | Actos | Thiazolidinedione (TZD) | Type 2 DM | Key Side Effects: edema, weight gain, upper respiratory tract infection | US Boxed Warning: may exacerbate congestive heart failure and Cl in NYHA Class III and IV |
liraglutide (SQ) | Victoza, Saxenda | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM, chronic weight management | Key Side Effects: nausea, vomiting, diarrhea, constipation | US Boxed Warning: may increase risk of thyroid c-cell tumor |
insulin detemir (SQ) | Levemir | Insulin, long acting | Type 1 DM, type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
insulin glargine (SQ) | Lantus, Toujeo, Basaglar | Insulin, long acting | Type 1 DM, type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
insulin NPH (SQ) | Humulin N, Novolin N | Insulin, intermediate acting | Type 1 DM, type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
insulin aspart (SQ) | Novolog | Insulin, rapid acting | Type 1 DM, type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
insulin lispro (SQ) | Humalog | Insulin, rapid acting | Type 1 DM, type 2 DM | Key Side Effects: hypoglycemia, weight gain | |
insulin regular (SQ, IV) | Humulin R, Novolin R | Insulin, short-acting | Type 1 DM, type 2 DM, DKA | Key Side Effects: hypoglycemia, weight gain | |
levothyroxine (PO, IV) | Synthroid, Levoxyl | Thyroid product | Hypothyroidism | Key Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance Other Notes: narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent | US Boxed Warning: not intended for use for weight loss |
thyroid, dessicated (PO) | Armour Thyroid | Thyroid product | Hypothyroidism | Key Side Effects: weight loss, palpitations, diarrhea, insomnia, heat intolerance Other Notes: narrow therapeutic index drug (therapeutic monitoring is recommended); not all generic products are therapeutically equivalent | US Boxed Warning: not intended for use for weight loss |
sitagliptin and metformin (PO) | Janumet, Janumet XR | sitagliptin: Dipeptidyl peptidase (DPP-4) inhibitor metformin (PO): Biguanide | sitagliptin: Type 2 DM metformin (PO): Type 2 DM, PCOS | Key Side Effects (Sitagliptin): headache, nasopharyngitis Key Side Effects (Metformin): diarrhea, nausea, vomiting | US Boxed Warning (Metformin): lactic acidosis |