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Infect. Diseases 3
Infectious Diseases 3
Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects/Other Notes | US Boxed Warning | Other Notes: |
---|---|---|---|---|---|---|
clindamycin (PO, IV) | Cleocin | Lincosamide antibiotic | SSTI, pharyngitis Activity against: MRSA | Key Side Effects: diarrhea, Clostridioides difficile diarrhea | US Boxed Warning: Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin, and may range in severity from mild diarrhea to fatal colitis | |
sulfamethoxazole and trimethoprim (PO, IV) | Bactrim, Bactrim DS | Sulfonamide antibiotic | SSTI Activity against: MRSA | Key Side Effects: nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), hyperkalemia, increased serum creatinine, hypersensitivity reactions | Other Notes: fixed ratio (5:1) of sulfamethoxazole and trimethoprim; dosing based on trimethoprim component | |
nitrofurantoin (PO) | Macrobid | Urinary antibiotic | Cystitis Activity against: Escherichia coli | Key Side Effects: nausea, pulmonary fibrosis (chronic use) | ||
gentamicin (IV) | ------- | Aminoglycoside antibiotic | HAP, pyelonephritis, neonatal sepsis Activity against: Pseudomonas aeruginosa, Escherichia coli | Key Side Effects: nephrotoxicity, ototoxicity | ||
vancomycin (IV, PO) | Vancocin | Glycopeptide antibiotic | IV: SSTI, HAP, meningitis, endocarditis, CRBSI PO: CDI Activity against: MRSA, Clostridioides difficile | Key Side Effects: nephrotoxicity, vancomycin infusion reaction | ||
metronidazole (PO, IV) | Flagyl | Antibiotic | Anaerobic infections, CDI Activity against: Bacteroides species, Clostridioides difficile | Key Side Effects: nausea, metallic taste, alcohol intolerance, peripheral neuropathy (long-term use) | ||
mupirocin (topical) | Bactroban | Antibiotic | MRSA decolonization | Key Side Effects: no major side effects |