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Infect. Diseases 2

Infectious Diseases 2

Generic NameBrand NamePharmacologic CategoryCommon IndicationsKey Side Effects/Other NotesUS Boxed Warning Other NotesOther Notes Cont.
meropenem (IV) Merrem Carbapenem CI: Meningitis, HAP, DFI, IAI Activity against: Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae Key Side Effects: diarrhea, hypersensitivity reactions, seizures with excessive doses
ertapenem (IV) Invanz Carbapenem CI: DFI, IAI Activity against: ESBL-producing Enterobacteriaceae Key Side Effects: diarrhea, hypersensitivity reactions, seizures with excessive doses
ciprofloxacin (PO, IV) Cipro Fluoroquinolone antibiotic CI: Pyelonephritis, HAP Activity against: Pseudomonas aeruginosa, atypicals Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warning: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Other Notes: take oral fluoroquinolones 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e., dairy products, calcium-fortified juices, oral multivitamins, mineral supplements); Other Notes Cont.: .... increased risk of aortic dissection or rupture, dysglycemias, CNS side effects (i.e., disorientation and delirium)
levofloxacin (PO, IV) Levaquin Fluoroquinolone antibiotic CI: CAP, pyelonephritis Activity against: Pseudomonas aeruginosa, Streptococcus pneumoniae, atypicals Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warning: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Other Notes: take oral fluoroquinolones 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e., dairy products, calcium-fortified juices, oral multivitamins, mineral supplements); Other Notes Cont.: .... increased risk of aortic dissection or rupture, dysglycemias, CNS side effects (i.e., disorientation and delirium)
moxifloxacin (ophthalmic, PO, IV) Ophthalmic: Vigamox, PO, IV: Avelox Fluoroquinolone antibiotic CI: Ophthalmic: bacterial conjunctivitis; PO, IV: CAP Activity against: Streptococcus pneumoniae, atypicals Key Side Effects: QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity US Boxed Warning: may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis Other Notes: take oral fluoroquinolones 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e., dairy products, calcium-fortified juices, oral multivitamins, mineral supplements); Other Notes Cont.: .... increased risk of aortic dissection or rupture, dysglycemias, CNS side effects (i.e., disorientation and delirium)
azithromycin (PO, IV) Zithromax, Z-Pak, Zmax Macrolide antibiotic CI: CAP Activity against: Helicobacter pylori, Chlamydia trachomatis, atypicals Key Side Effects: diarrhea, QTc prolongation
clarithromycin (PO, IV) Biaxin, Biaxin XL Macrolide antibiotic CI: CAP Activity against: Helicobacter pylori, Chlamydia trachomatis, atypicals Key Side Effects: diarrhea, metallic taste, QTc prolongation
fidaxomicin (PO) Dificid Macrolide antibiotic CI: CDI Activity against: Clostridioides difficile Key Side Effects: nausea Other Notes: do not use for systemic infections (no systemic absorption)
doxycycline (PO, IV) Vibramycin Tetracycline antibiotic CI: SSTI, CAP, tickborne diseases Activity against: MRSA, atypicals Key Side Effects: esophagitis (doxycycline only), photosensitivity Other Notes: may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; Other Notes Cont. ...... take oral tetracyclines 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e., dairy products, calcium-fortified juices, oral multivitamins, mineral supplements)
minocycline (PO, IV) Minocin Tetracycline antibiotic CI: SSTI, acne Activity against: MRSA esophagitis (doxycycline only), photosensitivity Other Notes: may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; Other Notes Cont. ...... take oral tetracyclines 2 hours before or 6 hours after products containing divalent or trivalent cations (i.e., dairy products, calcium-fortified juices, oral multivitamins, mineral supplements)
Created by: brookenicole1496
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