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Pre-Analytic Q's

Clin Chem I

QuestionAnswer
What are some examples of analytes that follow a circadian rhythm? melatonin corticosteroids acid phosphatase iron
What tests are affected by meals, specifically causing lower levels? chloride phospate potassium
What tests are affected by meals, specifically causing higher levels? gastrin glucagon growth hormone insulin ionized calcium triglycerides urine pH
What pre-collection factor can cause shift of fluids and changes in hormones? exercise/physical activity
What tests are affected by exercise? aspartate aminotransferase creatinine kinase uric acid
What tests are affected by stress? ACTH cortisol
How can posture impact pre-analytical variation? hemo-concentration of 5-8% can occur if standing prior to phlebotomy
How can alcohol impact pre-analytical variation? increases glucose by 20-50%
What are the effects of EDTA contamination during collection? increased potassium reduced calcium and magnesium reduced alkaline phosphatase and creatinine kinase
Order of draw? a) sterile, lt blue, SST, PST, lavender, green, red, gray b) sterile, lt blue, red, SST, PST, green, lavender, gray c) sterile, red, gray, lt blue, SST, PST, green, lavender d) sterile, red, gray, lt blue, PST, SST, lavender, green b) sterile, lt blue, red, SST, PST, green, lavender, gray
What are the effects of hemolysis on chemistry tests? increase of analytes from red blood cells increase/decrease of analytes from assay interference
Created by: alc6501
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