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Mobility Meds

QuestionAnswer
Dopamine Synthesis Levodopa/Carbidopa -Used for Parkinson's
Dopamine Synthesis Side Effects -GI upset (take w/ food) -Dyskinesia (jerky movements, tremors, head bobbing) -Orthostatic hypotension -Beta1 cardiovascular effects (tachycardia) -Psychosis (hallucinations) -Discolored sweat & urine -DON'T take with MAOIs (hypertensive crisis)
Dopamine Agonists Pramipexole Ropinirole Apomorphine -Used for Parkinson's
Dopamine Agonist Side Effects -Daytime sleepiness -Orthostatic hypotension -Psychosis -Impulse control disorder -Dyskinesia -Nausea -Dry mouth
Dopamine Releasers Amantadine -Used for Parkinson's
Dopamine Release Side Effects -CNS effects (dizziness, restlessness, confusion) -Anticholinergic effects (dry mouth, urinary retention, dehydration, tachycardia) -Skin discoloration
Monoamine Oxidase B Inhibitors Selegiline Rasagiline - Used for Parkinson's
Monoamine Oxidase B Inhibitor Side Effects -Insomnia (selegiline) -Hypertensive crisis (when taken with tyramine foods and medications)
COMT Inhibitors Catecholamine O Methyltransferase -Used for Parkinson's
COMT Inhibitor Side Effects -GI upset (take with food) -Urine discoloration -Rhabdomyolysis (muscle breakdown, pain, weakness, tendon pain, renal failure, monitor creatine) -Liver failure (RUQ pain, jaundice, nausea, fatigue, monitor LFTs)
Anticholinergics Trihexyphenidyl -Used to relieve tremors and rigidity
Anticholinergic Side Effects -N/V -Sedation -Drowsiness -HA -Dry mouth -Urinary retention -Dehydration -Photophobia -Tachycardia -Antihistamine effects (drowsy, sedation, dizziness) -start at lowest dose (doesn't affect muscle strength just spasm)
Muscle Relaxants & Antispasmodics Cyclobenzaprine Tizanidine Baclofen MS Carisporodol (centrally acting) Dantrolene MS (peripherally acting) Diazepam (central acting)
Muscle Relaxants & Antispasmodics Side Effects -Risk of seizures; do not give to pt with history of seizures (Baclofen) -Hepatic toxicity (Tizanidine and Dantrolene)
Corticosteroids Prednisone Methylprednisolone
Corticosteroid Side Effects -Long term use risk for bone loss and system infection -Peptic ulcer disease (GI bleeding, black tarry stools) -Edema -Weight gain -F & E disturbances -Myopathy
Anticholinergic Nursing Considerations -Increase fluids, bulk foods and exercise -Taper before discontinuation -Orthostatic hypotension precautions
Created by: NikkiLeigh83
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