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PMI A&P Ch3

PMI Anatomy & Physiology Ch3

QuestionAnswer
cells size and shape; human cells vary considerably in size; all are microscopic; cells different notably in shape
cytoplasm fluid in which all the organelles are in
organelles specialized structures within the cytoplasm
plasma membrane forms outer boundary of cell; composed of a thin, two-layered membrane of phospholipids containing proteins; is selectively permeable
ribosomes may attach to rough endoplasmic reticulum (ER) or lie in cytoplasm; made of two tiny subunits of mostly ribosomal RNA; manufacture enzymes and other protein compounds; often called the protein factories
endoplasmic reticulum (ER) network of connectiong sac and canals; carry substances through fluid cytoplasm;
golgi apparatus group of flattened sac near the nucleus; collect chemicals into vesicles that move from the smooth
mitochondria composed of inner and outer membrane sacs; involved with energy-releasing chemical reactions; contains one DNA molecule; ATP
lysosomes membraneous-walled organelles; contain digestive enzymes; have a protective function (eat microbes); formerly thought to be responsible for apoptosis (programmed cell death)
centrosome region od cytoplasm near nucleus; serves as microtubule-organizing center of cell; centrioles found within centrosome; paired organelles that lie at right angles to each other neat the nucleus; function in cell reproduction
microvilli* cell extension; small, fingerlike extension
flagella single projections extending from cell surfaces; much larger than cilia
nucleus surrounded by nuclear envelope; made up of two separate membranes; contains nuclear pores; contains nucleolus
chromatin unwound DNA; found throughout interphase; DNA is being used for macromolecule synthesis
chromosomes* tightly packaged DNA;
relationship of cell structure and function every human cell has a designated function; some help maintain the cell; others regulate life processes of the body itself; specialized functions of the cell differential depending on the number and the number and type of organelles
passive transport does not require added energy; result in movement "down a concentration gradient"
diffusion substances scatter themselves evenly throughout an available space; it is unnecessary to add energy to the system; movement is from high to low concentration
osmosis diffusion of water (when some solutes cannot cross the membrane); substance always tries to equalize itself
dialysis diffusion of solutes; concentration
filtration movement of water and solutes caused by hydrostatic pressure on one side of membrane; responsible for urine formation
active transport process* occurs only in living cells; movement of substances is "up the concentration
ion pumps a protein complex in the cell membrane; ion pumps use energy from ATP to move substances across cell membranes against their concentration gradients; example: sodium-potassium pump and calcium pump; some work with other carries
phagocytosis a protective mechanism often used to destroy bacteria
pinocytosis used to incorporate fluids or dissolved substances into cells
phagocytosis and pinocytosis both are active transport mechanisms because the require cell energy
cystic fibrosis characterized by abnormally thick secretions in the airways and digestive ducts, results from failed Cl- (chloride ion) transport
cholera a bacteria infection that causes Cl- and water to leak from cells lining the intestines, resulting in severe diarrhea and water loss
cell growth and reproduction DNA molecule resembles a long, narrow ladder twisted round and round its axis; shaped in a double helix; each molecule is made of a sugar (deoxyribose), bases, and phosphate units; bases are nitrogen-containing chemicals: adenine,thymine,guanine,&cytosine
AT adenine attached to thymine
GC cytosine attaches to guanine
DNA complementary base pairing: each step of DNA ladder contains a base pair; adenine-thymine or cystonine-guanine; a gene is specific segment of base pairs in a chromosome
DNA location nucleus of the cell
protein synthesis occurs in the cytoplasm of the cell, thus genetic information must pass from the nucleus to the cytoplasm
transcription* making a copy of the blueprint; double-stranded DNA separates to form messenger RNA (mRNA); each strand of mRNA duplicates a particular gene )base
translation involves synthesis of proteins in cytoplasm by ribosomes; requires use of information contained in mRNA; codon: series of three nucleotide bases that ace as a code for a specific amino acid
abnormal DNA is inherited, or that results from damage, is often the basis of disease
factors that cause damage to DNA molecules chemical or mechanical irritant, radiation, bacteria, and viruses
**mutagenic substances we are exposed to in the OR **
*DNA replication process by which each half of a DNA molecule becomes a whole molecule
mitosis process in cell division that distributes identical chromosomes into each of the new cells formed when the original cell divides
prophase first stage; chromatin granules become organized; chromosomes appear; centrioles move away from nucleus; nuclear envelope disappears, freeing genetic material; spindle fibers appear
metaphase second phase; chromosomes align across center of cell; spindle fibers attach themselves to each chromatid
anaphase third stage; centromeres break apart; separated chromatids no called chromosomes; chromosomes are pulled to opposite sides of the cell; cleavage furrow develops at end of anaphase
*telophase fourth stage; last stage; cell division is completed; nuclei appear in daughter cells; nuclear envelope and nucleoli appears; cytoplasm is divided (cytokinesis)
hypertrophy increase in size of individual cell; increasing size of tissue
atrophy decrease in size of individual cells; decreasing size of tissue
hyperplasia increase in cell reproduction, increase size of tissue
anaplasia production of abnormal, undifferentiated cells
benign cancer encapsulated in one area; can still grow but can not go to different tissues
Created by: cdilello
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