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Stack #34989

A&P11-Class Notes Pg 23 Blood Pressure

QuestionAnswer
Systolic (in BV ch on BP) refers to when you contract
diastolic (in BV sh on BP)refers to resumption of normal flow
blood flows thru a system of: closed channels
Blood always flows from regions of higher: pressure to lower pressure
Mean (avg) pressure in aorta is about: 100 mm Hg
Pressure from aorta continually decreases rapidly thru the arterial sys & more slowly thru the venous sys
Normal BP is 120 over 80 ....
Blood flows from aorta to: arteries to arterioles
cont'd blood flow: arterioles to: capillaries to venules
cont'd blood flow: venules to veins to: the vena cava to the R, atrium
Blood pressure is the pressure exerted by blood: on the wall on any BV
clinical sense:systolic = pressure during ventricular systole when B is moving into the arteries
Clinical sense: diastolic = pressure of B in arteries after ventricular systole
Homeostatic mechanisms regulate cardio vascular activity to ensure: that tissue B flow (tissue perfusion) feets the demand for oxygen and nutrientsbl
3 variables of homeostatic mechanisms are: cardiac output, blood volumn, peripheral resistance
Cardiac output is amt of B ejected by the L ventricle every minute
Blood Volumn is: nORMAL VOLUMN IS 5 LITERS
a +or - in B volumn will: affect pressure
Peripheral Resistance is resistance to B flow by the force of friction bet: blood & the walls of the vessel it is traveling thru
Cardiovascular Control Mechanisms: 3 Autoregulation, Central Mechanisms, and Endocrine Factors
Which of the 3 is lst: autoregulation is Local Controls is is 1st response
Autoregulation is: an automatic local adjustment of Blood flow in a perticular part of body.
in autoregulation cells respond to local changes (ie low oxygen levels) by releasing: vasodilator substances or vasoconstrictor substances
examples of vasodilator substances are: potassium ions, lactic acid & carbon dioxide
examples of vaso constrictor substances are: prostaglandins and endothelins released by damaged endothelial cells
if Cardio autoregulation at the local leval fails then: activation of control mechanisms II or III will occur
Cardio control mechanism II is: Central Mechanism (neural controls) the electrical system
Central mechanisms include 4 types: Higher Brain Centers, Vasomotor center, Baroreceptors and Chemoreceptors
In higher brain centers typa, the cerebral cortex and hypothalamus regulate BP by: sending impulses to the vasomotor center during times of stress, anger, ets. This results in vaso constriction and hence, increased BP.
Vasomotor Center consists of a culster of: sympathetic neurons in the medulla oblongata. It controls BV diameter by providing vaso constriction & vaso dilation regulation.
The vasomotor center sends inpulses to the vasomotor fibers which: are efferent fibers of the SNS located in smooth muscles of BV walls. When stimulated they produce norepinephrine.
peptide a protein fragment
NO is a gas
norepinephrine in turn regulates smooth muscles in BV's: to provide vasoconstriction
ACh stimulates the release of NO by: endothelial cells in the area in question.
The release of NO gas relaxes muscle cells, thereby causing vasodilation
The resistance of a maximally constricted arteriole is: 80 times that of a fully dilated arteriole
Baroreceptors = sinus stretch
Baroreceptors are specialized receptors: mechano receptors or presso receptors that monitor the degree of stretch in the walls of expandable organs. r
Examples of baroreceptors: aortic sinuses (provide aortic reflex) in pockets in the wall of the ascending aorta AND carotid sinus near the base of the internal carotid arteries of the neck
Chemoreceptors are: chemical body receptors
Chemoreceptors are sensory neurons that are sensitive to: chemicals in the blood.
chemoreceptors are named: carotid body and the aortic body
The carotid body is located at the bifurcation of the common carotid arteries
The aortic body is located in the aortic arch
chemo receptors are sensitive to blood levels of : oxygen, carbon dioxide and hydrogen ions.
chemoreceptors are sensory neurons that: help regulate the respiratory rate
The 3rd control mechanism is the: Endocrine System
The Endocrine system is: A chemical System, local or central
Hormones are: chemical regulators produced by specialized endocrine glands as well as other cells and body tissues
Example: ANP, a hormone produced by: the heart, not by a regular endocrine gland
The hormone producing cells/tissues/organs of the body provide: chemical regulation
Hormones Associated with the cardio sytem incl: 5 Antidiuretic hormone (ADH), Angiotensin II, Erythropoetin (EPO), Atrial Natriuretic Peptide (ANP or ANF), Endothelium-derived factors (EDF),
Antidiuretic Hormone -ADH: long term regulation of B pressure & volumn.
ADH is released from the posterior: pituitary & stimulates water conservation in the kidneys. Thus B volumn is conserved
Angiotensin II is for long-term regulation: long-term regulation of blood pressure and blood volumn.
Angiotensin II is a powerful vasoconstrictor & it appears in blood following the release of renin from kidney cells (renin-angiotensin pathway)
Erythropoetion EPO for long term regulation of B pressure & volumn. It is released from kidneys to stimulate RBC formation if/when oxygen levels fall to low.
Atrial Natriuretic Peptide (ANP or ANF) Provides long term regulation of Blood pressure and blood volumn
ANP also encourages fluid: loss, reduces blood pressure & blood volumn, inhibits thrist and lowers peripheral resistance
Endothelium-derived Factor EDF- assist w/ local blood flow
EDF is a group of chemical that are: produced by endothelial cells
EDF s act as either vaso constrictors or vasodilators
Examples of EDF's include: PDGF (prostaglandin-derived growth factor, NO (nitric oxide, a vasodilator) nad endothelin (a vasoconstrictor)
 

 



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