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Opioid Agonists

NERVOUS SYSEM: Synthetic Narcotics

QuestionAnswer
Meperidine (Demrol) Mu agonist used for relief of acute pain such as pain occurring after orthopedic procedures. May be combined with a tranquilizer for use as an anesthetic. Naloxone preferred agonist
Oxymorphone (Numorphan and Opana) Semisynthetic opioid that is a mu agonist. Used for restraint in dogs, diagnostic procedures, minor surgeries. Can be combined with tranquilizers to produce neuroleptanalgesia. Naloxone is antagonist
Butorphanol tartrate (Torbutrol, Torbugesic) Synthetic opioid agonists/antagonist. Agonist activity exerted on kappa and sigma receptors. Antagonist activity on mu receptor. Used for analgesia and antitussive effects.
Fentanyl Opioid agonist used to control chronic pain
Hydrocodone bitartrate (Hycodan, Tussigon) Opioid agonist used as an antitussive agent in dogs
Etorphine (M-99) Produces analgesic effects. Lethal if injected and can be absorbed through the skin. Restricted for zoo and exotic animals. Can be reversed by antagonist dipronorphine
Pentazocine (Talwin) Partial opioid agonist for pain relief in horses and dogs
Diphenoxylate (Lomotil) Combined with atropine for use as an antidiarrhea agent
Apomorhpine Dopamine agonist with the principal effect of inducing vomiting by stimulating the chemoreceptor trigger zone in the brain. Often administered by placing a portion of a tablet in the conjunctival sac for absorption
Methadone (Dolophine) Primary use is the treatment of colic pain in horses
Codeine Use as an antitussive in dogs
Carfentanil (Wildnill) Used to induce wildlife anesthesia
Buprenorphine (Buprenex) Partial mu agonist-antagonist. Potent analgesic used in several small animals, especially the cat. Longer duration of action than butorphanol.
Buprenorphine (simbadol) SQ injection 1x/day for 3 days in cats. Provides 24hr continuous pain control after postoperative pain with surgical procedures
Adverse Side Effects Respiratory depression, excitement (Cats and horses), nausea, vomiting, diarrhea, defecation, panting, convulsions
Created by: lauren97
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