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Ventricular/Spinal
| Question | Answer |
|---|---|
| What is venticular system | Elaboration of lumen of cephalic portion of neural tube |
| Development that parallels brain | venticular system |
| Ventricular system consists of | Lateral, 3rd, 4th, Cerebral aqueduct, Intraventricular foramina |
| Telencephalic vesicles cavity b/c | lateral ventricles |
| Diencephalic cavity b/c | 3rd ventricle |
| Rhombencephalic cavity b/c | 4th venticle |
| Mescencephalon cavity b/c | cerebral aquaduct |
| What is Intraventricular foramina | opening between the lateral ventricles, and 3rd ventricules |
| Ventricular system is lined with | ependymal cells |
| Each venticule is composed of | internal layer of ependyma, and outher layer of delicate Pia matter |
| In each ventricle blood vessel invaginate to form | choroid plexus |
| What is medial aperture AKA | Foramen of Magendie |
| Opens in caudal roof of 4th ventricle during develops form a communication betwen | the venticular system and subarachnoid space |
| Medial aperute and Luschka---form | communication beween the ventricular system, and subarachnoid space during development |
| CFS is produced by | Choroid plesuses |
| Choroid plexuses located in | lateral and third venticules |
| CFS exits the venticular system thought | the foramina of 4th, and passes into subarachnoid space |
| The CSF is absorbed into venous systme by | arachnoid villi |
| Arachnoid villi located in | superior sagittal sinus |
| Congenital hydrocephalus | dilation of ventricular system |
| Results do to enlarged ventricules during prenatal development | congenital hydrocephalus |
| Dilation of ventricles results from | the flow of CSF being obstructed during development |
| Primary obstruction of CSF | cerebral aquaduct |
| Congenital atresia | failure of cerbral aquaduct to form |
| Stenosis | obstuction of cerbral aquaduct from cellular debris |
| Stenosis is due to | infection |
| Intravaventriculat hemorrage can result in | can block the cerebral aquaduct |
| Dandy-Walker malformation | patients have a cystic dialtion of 4th with aplaisa of cerebellar vermis |
| PNS develops mostly from cells of the | neural crest |
| Neural crest cells arise from | the lateal edge of the neural plate |
| Neural crest cells detach and move | to locations lateral to neural tube |
| Specizlized epiderman cells found in developing head region | Placodes |
| CN 5, 7,9,10 all have | sensory ganlia that orginate from neural crest adn placode cells, and are psuedonunipolar |
| Pseudouniplar cells are derived from | neural crest cells |
| Each spinal nerve and ganglion are associated with | a somite o |
| Somites grow out to form parts of the body's | CT and musculature |
| How dorsal root ganglia grow distally | use the ECM of tissues as a guide |
| Autonomic neurons of the digestive tract are formed by | neural crest cells |
| Nueral crests cells that migrate from rhombencephalon | autonmic neurons of disgestive tract |
| Autonomic neurons of digestive tract receive innervation from | Vagus nerve in adult |
| Visceral Neural crest cell develop into | automic neurons of the desecnding colon and neurons of pelvic structures |
| Neural crest cells of colon and pelvic arise from | sacral cord levels during 2nd neurulation |
| Schwann cells are derived from | neural crest cells |
| Schwann cells migrate in | a segmental fashion, |
| Schwann cells growth with the | peripheral nerve fibers this will eventually ensheathe |
| Cell involved in development of CNS | neuroblasts |
| CNS neuroblasts develop at | the ventricular surfaces of developing brain |
| Ventricular surface of developing brain AKA | luminal surface of the neural tube |
| Why does neural tube thicken during development? | Dividing cells cluster @ ventricular surface 2. marginal zone |
| 2 main lingeage of CNS | Neuroblastic and Glioblastic |
| Neurblastic generates | neurons |
| Glioblastic are | precursors of radial glia, asto, and oligodendrocytes |
| Differentiation of Glial cells is controled by | Growth factors |
| Types of Glial Growth factors | PDGF Cillary nerotrophic factor, and FBF |
| Adult sinal cord gray matter is shaped | as a buttergyl |
| Spinal cord gray matter consits of | anterior and posterior horns |
| Ar some levels of the spinal cord, there is also | an intermediate zone, and a lateral horm |
| The intermediate zone and lateral horn lie | halfway between teh posterior and anterior horns |
| What develops from cadual portions of neural tube? | spinal cord |
| The neural canal will become | the central canal of the spinal cord |
| Between 4th and 20 weels give rise to spinal cord b/c | burst of proliferatoin in ventricular layer |
| Nueroblasts of spinal canal will migrate to form | 4 longitudinal plates |
| 4 longitudinal plates will become | the gray matter of spinal cord |
| 2 anterior located cell massses | basal plate |
| 2 posteriorly located ell masses | alar plate |
| Basal and Alar plates are separated by a longitudinal groove | sulcus limitans |
| Basal plate develops into | anterior horn of spinal cord |
| Alar plate develops into | posterior horn of spinal cord |
| The lateral horn orginates | from the interface of alar and basal plates |
| Basal plate development controls | axons of motor neurons Anterior horn===GSE Lateral horn--GVE |
| anterior roots of basal plate development will innervate | peripheral structures |
| Anterior horn motor neurons innervate | GSE skeletal muscle |
| Lateral horm motor neurson project to | autonmic ganglie |
| Lateral horn motor neurons innervate | GVE |
| GSE and GVE are distinct | lonitudinal cell colums in gray matter of BASAL Plate |
| GSE column runs | full length of spinal cord |
| GVE colum runs | from T1-L2 |
| Intermediolateral cell column | GVE column fromT1-L2 |
| GVE also runs | S2-S4 |
| Sacral visceromotot nucleus | GVE colum running froms2-s4 |
| Alar plate development is where | neurons receive sensory, GSA, and GVA |
| Sensory neurons in peripheral process innervate the skin, and the R's in joint capusles, tendons, and muscles called | GSA |
| Sensory neurons that innervate R's in visceral structures | GVA |
| Somites subdivide into | Sclertomes-vertebrate, Dermatomes, form skin, and myotomes form muscles |
| Spinal cord retain its shape from ____until adulthood | 3rd trimester |
| Vertebral column grows slightly faster than | the spinal cord |
| What forms the cauda equina | results from differential growth of vertebral column |
| Neural Crest cells give rise to both | Nueronal and non-neuronal structures |
| Postganglionic sympathetic, and parasympatetic are dervired from | neural crest cells |
Created by:
talkglitter2486