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Equation Review
FA Important Equations
Question | Answer |
---|---|
Volume of distribution (Vd) | (amount of drug in the body) =------------------------------------ (plasma drug concentration) |
Half-life (t 1/2) | (0.7 x Vd) = ---------------- ( CL) |
Drug clearance (CL) | ( rate of elimination of drug) = -------------------------------------- ( plasma drug concentration) |
Drug clearance (CL) | = (Vd x Ke) (Ke is the elimination constant) |
Loading dose (LD) | (Cp x Vd) = ---------------- F |
Maintenance dose (D) | (Cp x CLx t) = ------------------- F |
Sensitivity | TP = --------------- (TP + FN) |
Specificity | TN = ------------------ (TN + FP) |
Positive Predictive Value (PPV) | TP = -------------- (TP + FP) |
Negative Predictive Value (NPV) | TN = -------------- (FN + TN) |
Odds ratio (for case control studies) (OR) | a/c ad = ------- ==> --------------- b/c bc |