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KIN 3600
Lec 10
Question | Answer |
---|---|
Cori cycle | Lactate produced by a muscle and diffuses into the blood circulation; liver picks up and dehydrogenizes lactate to pyruvate then converts pyruvate back to glucose; glucose leaves liver back into circulation and muscle picks up glucose. G->P, P->Lac |
How much lactate is oxidized following exercise? | 70% -used as substrates by the heart and skeletal muscle |
how much lactate is converted to glucose in the live? | 20% |
how much lactate is converted to amino acids in the liver? | 10% |
Type 2 muscle cells | -lactate producing cell -Fast glycolytic fibers -Main metabolic pathway |
1 lactate cause of fatigue | -pH decreases inactivates enzymes, PFK, Fats -Muscle restricts fats by recombining FFA with glycerol |
Following a lactogenic exercise, lactic acid | is removed more rapidly with light exercise compared to passive rest during recovery |
optimal intensity | 30 – 40% VO2 max |
No exercise | Slow v blood lactate |
Light exercise | Faster v blood lactate concentrates |
The main adaptations to short duration high intensity lasting less than 8-10 seconds (100m dash) | ^ 25% ATP, 40% CP ^ fuel storage = ^ duration ^ 30% ATPase, 20% MK, 36% CPK Top speed remains SAME |
Main adaptations to short duration high intensity training 20 to 60 sec | -mainly fueled by anaerobic glycogenolysis - ^ muscular glycogen - ^ duration = improved performance - ^ 83% key glycolytic enzymes (PFK) - ^ top speed |
Main adaptations to endurance training (800m-marathon) | - ^ 26% myoglobin - ^ 120% number and 40% size of mitochondria - ^40% activity and concentration in TCA & ETC - ^ glycogen storage 2.5 x - ^ fatty acids utilization |
Main adaptations to High-Resistance strength training (5 months) | -28 % increase in strength -5.1 % increase in CP concentration -35.2 % increase in Creatine concentration -17.8 % increase in ATP concentration -32 % increase in Muscle Glycogen concentration |
Steady state exercise | constant unchanging |
Maximal Exercises | interval environment ^ till fatigue |
Fastest system to supply energy | ATP & CP |
ATP v = v speed | ATP ^ = ^ speed |
Steady State | O2 consumption curves linearly meets ATP demand keeping -1.5 L-min |
O2 deficit | How much oxygen should have been utilized to make exercise aerobically |