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Path-Inf. Skin Dis

Keep it simple

spongiotic dermatitis eczema(boiling over) increase in inflammation resulting in widened spaced filled with fluid b/t keratinocytes via lymphocytes and macrophages
Allergic contact dermatitis es. poison ivy treat with corticosteroids
atopic dermatitis more chronic and persistant spongiotic dermatitis via inf. or irritation
Foliculitis genetic and androgenic influence keratin and sebum clog follicles resulting in proprionibacterium acnes resulting in open and closed comedones (white and blackheads)
Leukocytoclastic vasculitis immune complexes lodge in the vascular walls (venule) resulting in complement cascade and damage with palpable purpura
where is leukocytoclastic vasculitis found on the lower extremities, GI, Kidney, and CNS
Erythema Multiform eruption of the skin
Steven Johnson Syndrome TEN (toxic epidermal necrolysis) mucus membrane involvement and shedding of the skin via Herpes, infectious agents, and drugs
what is the pathology of Steven johnson syndrome 1) degeneration of the basilar layer 2) eosinophilic apoptotic bodies 3) perivascular lymphocyte infiltrate
Impetigo Staph and Strep infections honey colored cysts can lead to post strep glomerulonephritis
how does impetigo happen neutrophils aggregate below the statum corneum
syphillis treponema pallidum Chancre (painless) resolves in 6 weeks followed by condyloma lata and maculopapular eruptions of palm and soles and then endarteritis and ischemia
what are the systemic lesions associated with syphilis liver, mucus membrane, meninges,
Gumma characteristic nodules of tertiary syphilis
what stain do you use to see spirochetes warthin starry stain
what are the infiltrative cells with syphilis infections plasma cells
Verrucae warts via HPV can spread with superficial trauma
Verruca vularis most familiar can find anywhere with a rough surface
verruca plantaris flat small lesion that appears as multiples on the feet
condyloma accuminatum papillary lesion in anogenital region verucae are generally benign
Bowenoid Paulosis and Epidermodysplasia verruciformis precancerous lesions from HPV (think HPV and koilocytes when hyou see verruciformis) just remember bowenoid HPV
Molluscum contagiosus flesh colered papules with central keratotic core spread via pox virus
moluscum bodies and inclusion bodies molluscum contagiosum
varicella zooster virus and Herpes 1 and 2 all herpes from dorsal root ganglia confined within the DERMATOME that root supplies
multiple gun metal gray nuclei Herpes and varicella zooster
Superficial Fungal infection Dermatophiytes superficial red scaly patches named by region
tinea capitus a superficial fungal infection that can cause hair loss
candida albicans papules and pustules in the intertriginous area (those that rub together)
Malassezia furfur (hypal form of pityrosporum cause white scaly patches on the trunk
malasseazia minimal change with multiple yeast forms
dermaphytes and candida and malassezia furfur are all superficial fungal infections
how makes yeast out of the superficial fungal infections candida and malassezia
who of the superficial fungal infections makes hyphea dermophytes (candida make pseudohyphea
scabies transmitted via an arthropod bite/sting
sarcoptes scabiei female burrows in finger webs and genitals with intense itching
Created by: jmuame03