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Monckeberg Medial Sclerosis degenerative calcifications of the Large and Medium muscular artery vessel wall media layer
where are atherosclerotic aneurysm found distal aorta and common iliacs
where is a syphilitic aneurysm found ascending aorta and arch
where are dissecting aneurysms found in the proximal aorta from an intimal tear 1 to 2 cm above the aortic valve
what are varicose veins dilated superficial veins
what causes deep vein thrombosis stasis and or inflammation
what is lymphangitis inflammation of the lymphatics usually in an area of previous trauma via GAS
a capillary hemangioma is called a birthmark
a cavernous hemangioma is called a port wine stain (large vascular channels)
where are angiosarcomas found in the skin and soft tissue rare malignant neoplasm of the endothelial cells
angiosarcomas of the liver are associated with? environmental carcinogens (arsenic and vinyl chloride)
Kaposi Sarcoma on skin or mucus membranes, GI and Lungs in AIDS patients Herpes Simplex 8
Acute Mastitis inflammation of the breast due to staph. aureus in the babies mouth
Lactiferous mastitis another name for acute mastitis (inflammatory condition of the breast from feeding)
Granulomatis Mastitis Inflammation caused by infections that can’t be cleared like Tb, Sarcoid, or foreign material
Mammary duct Ectasia infiltration of histiocytes and secretions with fibrosis and inflammation subareolar
what causes fat necrosis fibrocystic change, ductal hyperplasia and radial scar
what is fibrocystic change not a disese dilations of the ducts with apocrine metaplasia and fibrosis
what is sclerosing adenosis whe tne terminal ducts and acini proliferate with fibrotic stroma seen in those with fibrocystic change
Ductal hyperplasia alone or with fibrocystic change (can progress to cancer if proliferation is atypical)
fibroadenoma benign neoplasm presents a mass in 20-30 y/o women
what are the benign neoplasms of the breast fibroadenoma, intraductal papilloma, nipple papilloma
Radial Scar often confused with malignancy but is benign fibroelastic core with radiating ducts and lobules
intraductal papilloma large duct with subaereolar location and discharge
nipple papilloma subaereolar mass with discharge and errosion that looks like Padget’s disease
what are the carcinomas in situ of the breast ductal, lobular and padgets
how is ductal carcinoma distributed usually unifocal with risk on the ipsilateral side
what carcinoma in situ makes you watch only the affected side ductal carcinoma in situ
how are lobular carcinomas in situ distributed multifocal with worry about both breasts
which in situ carcinoma makes you worry about both breasts lobular carcinoma in situ
padgets disease tumor confined in the epithelium of the nipple
50-70% of invasive breast cancers are? invasive ductal carcinomas
how do invasive lobular carcinomas present not as a mass they are too diffuse and lack desmoplasia (fibroblasts)
inflammatory carcinoma not distinct but appears a a peu de orange with spread over the skin of the breast
Phylloid turmo leaf like tumor that occurs around age 45 with hypercellualar overgrowth of bland ductal elements
what is gynecomastia gland or stromal hyperplasia in men
Libman Sacks Endocarditis associated with SLE (50% of lupus patients) may embolize or be colonized
Carcinoid Heart disease plaque like pearly whit fibrous thickening of the RV endocardium they can secreate bioactive amines and will mimic sympathetic nervous system activation
AD Dilated Cardiomyopathy most common primary cause of cardiomyopathy affects sarcoglycan, troponin and myosin
X linked dilated cardiomyopathy affects the dystrophin gene on X21 in teen boys (related to MD) no transmission of force
Mitochondrial primary Dilated cardiomyopathy accounts for? <10% of primary cardiomyopathy
Pregnancy induced secondary dilated cardiomyopathy when? third trimester or postpartum
Secondary metabolic Dilated cardiomyopathy is caused by Hyper OR Hypothyroid or Thiamine Deficiency
localized amyloidosis of the heart restrictive cardiomyopathy in the elderly pale heart with amyloid around the vessels and myocardium
Systemic amyloidosis affecting the heart the heart most common cause of death in people with plasma cell dyscrasia
Obliterative restrictive Cardiomyopathy low volume low compliance cardiomyopathy via endocardial enlargement
Loeffler’s endomyocarditis Obliterative restrictive cardiomyopathy caused by hypereosinophilia common in the subtropics of africa
endocardial fibroelastosis Restrictive obliterative cardiomyopathy with normal wall but large endocardium (10x normal) with cartilage like fibroelastic endocardial thickening common in those age 0-2 Left more than right
Primary causes of myocarditits viral usually viral (coxsackie A/B, polio, Echo, influenza, CMV, HSV
primary bacterial cause of myocarditis corynebaterium, borrelia and rickettsial/fungal in immunosuppressed
Primary pericarditis is usually viral
Hemorrhagic pericarditis is due to? Tb or tumor and always scars
fibrinous pericarditis is due to MI or Radiation (bread and butter appearance)
serous pericarditis is due to autoimmune or uremia
difference between chronic adhesive and chronic constrictive adhesive pulls and dilated the heart which constrictive (scar) enclosed and decreases the size of theheart
which pericarditis can progress to chronic supporative, hemorrhagic and caseous
most common primary cardiac tumor Myoxoma Mostly left atrium this is a friable tumor
what is the most common primary tumor in children (cardiac) rhabdomyosarcoma associated with tuberous necrosis
Created by: jmuame03