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BACT: Strep pneumo
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Question | Answer |
---|---|
shape of Strep Pneumo | lancet |
S. Pneumo is what shape | diplococci |
B or alpha hemolytic | Alpha on s. pyrogene is B |
how do you diagnose S. Pneumo | Blood, Optochin sensitive, Bile solubility test, Qeulling reaction |
type of capsule | polysaccharide |
how many serotypes are there of the strep pneumo capsule | 80 |
Rough mutants? | lack capsule and are not virulent |
what is pneumolysis | thiol activated hemolysis |
Strep pneumo is the number one cause of? | community acquired pneumonia, bacteremia in infants, adult meningitis, otitis media, conjunctiva |
Strep pneumo is number 2 cause of ? | meningitiis in kids over 2 |
diseases caused by strep pneumo | lobar pneumonia, meningitis, otitis media, sinusitis, chronic bronchitis, conjunctiva |
what percent of adults have S. pneumo as normal flora | 20-70% |
how do you treat strep pneumo | B lactams penicillin( 42% resistant) so erythromycin and vanco for resistant forms |
how can you tell strep pneumo from strep viridans | optochin sensitive = pneumo |
how does Strep pneumo casue meningitis | bacteremia or trauma |
vaccines for strep pneumo | pneumovax ( T ind. greater than 2) and Prevnar (Conj for those who need to use T cells kids under 2) |
mortality of s. pneumo if treated | 25% only 5% with treatment |
mortality of those over 50? over 70? | 30% over 50 ---- 60% over 70 |
how does strep pneumo avoid phagocytes | kills them with pneumolysin and capsule |
most virulent capsule | 3 |
what percent of patients become bacteremic | 30% |