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Micro 5-1

Duke PA micro

What are the medically important gram positive rods? bacillus, corynebacterium, erysipelothrix, gardnerella bacillus
What is bacitracin produced from? B. subtilis
What are the virulence factors in bacillus? endospores, enterotoxins
What are the important species? B. anthracis, B. cereus, B. subtilis, B. sterothermophilus
What is the etiological agent of anthrax? B. anthracis
What are the three clinical presentations of anthrax? cutaneous, gastroenteritis, inhalation
What are the two clinical presentations of B. cereus? gastroenteritis (mediated by enterotoxins) and ocular (trauma --> rapid, progressive destructions)
What is the classic radiographical presentation of anthrax? widened mediastinum
Corynebacterium genus of Gram positive rods, often irregularly shaped
How well do corynebacterium grow on lab media? readily
What is the etiologic agent of diphtheria? C. diphtheriae
Where is C. diphtheriae found in normal flora? skin, GI, GU and respiratory tracts
diptheroids corynebacterium
What two genera are often grouped together in microbiology because both are aerobic rods with similar microscopic morphology? erysipelothrix, listeria
erysipelothrix small, thin rods that form long filaments, grows slowly in vitro, little known about its virulence factors
Listeria small, paired coccobacilli
Out of the 3 species of erysipelothrix found in humans, which is associated with disease? E. rhusiopathiae
Where is erysipelothrix colonized? many animals, especially turkey, swine, fish
How do erysipelothrix infections move to humans? zoonotic, cutaneous - butchers, farmers, vets
What does systemic form of erysipelothrix cause? rare - usually endocarditis
Where is listeria widely found? in animals
What other places can listeria be found? soil, water, vegetation, variety of mammals, fish, fowl
how is human disease from listeria transmitted? by contaminated food, vertical, zoonotic
Who is at risk for listeria infection? neonates, elderly, pregnant women, cancer/transplant patients
What are the virulence factors of listeria? hemolysin, listeriolysinO, ability to survive in cold temperatures
What are the medically important anaerobic gram positive rods? actinomyces, clostridium, lactobacillus, mobiluncus, propionbacterium
Where do anaerobic medically important gram positive rods typically colonize? skin and mucosal surfaces
actinomyces filamentous morphology; resembles hypae
What is the most common actinomyces infection in humans? A. israeli
Where do actinomyces typically colonize in humans? upper respiratory, GI and female genital tracts
What does actinomyces cause? low virulence - cause infection when mucosal barriers are disrupted, often chronic
Clostridium spore formers, spores more prominent in some species than others
Where is clostridium ubiquitious? soil, water, human GI tract
What are the four medically important clostridium infections? C. perfringens, C. botulinum, C. tetani, C. difficile
Created by: ges13