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biochem 2 - 2
Biochem 2 - 2nd exam
Question | Answer |
---|---|
what does an increase in acetyl coa do to GNG? why? | Stimulates... inhibits pyruvate DH so pyruvate is more likely to go to GNG |
Where does Acetyl CoA + OAA ----- citrate take place? | Matrix of mito |
Citrate ---- CoA + OAA takes place? | cytosol |
Glycogen gets acted on by glycogen phosphorylase and Pi give you what? | Glucose 1P |
In glycogen breakdown, glucose 1P is converted to what via what enzyme? Why is it converted to this? | 1. Glucose 6P via phophoglucomustase 2. Because G6P cam then go to glycolysis and make ATP |
What cycle creates G6P to enter a glycolysis cycle? | Glycogen breakdown... GNG |
Synthesis of glucose come from non carbohydrate precursors...name them | Lactic acid, amino acids, glycerol |
Pyruvate carboxilase is located in the ___ of the kidney and liver. | mito |
Malate shuttle : pyruvate to OAA via what? Where does this occur? | Pyruvate carboxylase...INNER MEMEBRANE OF MITO |
How does OAA get out of the inner membrane of the mito to the cytosol for PEP carboxikinase to work on it? | Malate shuttle |
Alpha keta acids enter into krebs and form what? This is a direct precursor to what? | OAA - Pyruvate |
Substance that makes ketone bodies | Acetyl CoA or things that can make Acetyl CoA |
3 things that can turn into Acetyl CoA | Fats through OHOT Citrate through citrate lyase and Pyruvate through pyruvate DH |
When we are ketotic, what enters the krebs? What spills over? What is made? What will this prevent? | 1. Fatty acids 2. Acetyl CoA 3. Ketone bodies 4. Protein catabolise (amina acid degregation) |
The overcoming of pyruvate kinse requires 2 steps... where do they take place? | step 1 = Inner membrane of mito in liver Step 2 = Cytosol of liver |
What does fatty acid synthse do? | CRDR |
What does Acyl CoA DH do? | OHOT |
What makes acetyl CoA? | Pyruvate ---PDH--- Acetyl CoA |
Ketones are primarily created from __ and can be oxidized to make ___? | Fat, ATP |
What cycle takes lactate, sends it to the liver to make glucose? | Cori Cycle |
In the morning, what is being tunred into glucose? | Amino acids |
What cycle takes alanine to the liver and makes glucose? | Glucose - Alanine cycle |