click below
click below
Normal Size Small Size show me how
rsrch pharm2-7
RESPIRATORY & NSAIDS
| classes & drugs | Indications and MOA and SE |
|---|---|
| Albuterol (roventil, Venolin) | beta 2 bronchodialator |
| Albuterol (roventil, Venolin) | tx for asthma and COPD |
| Epinephrine (Adrenalin) | beta agonist dialators- beta1 and beta 2; beta 1=arteriolar constriction =nasal decongestant |
| Epinephrine (Adrenalin) | asthma or COPD tx |
| ANTICHOLENRGICS | prevent Ach from binding to receptors=blocks bronchoconstriction |
| Montelukast (Singulair) | Antileukotriene-- blocks action of LT (cause inlfammation, bronchoconstriction, and mucous production) |
| Montelukast (Singulair) | prophylactic with chronic asthma & seasonal allergic rhinitis |
| Bechlomethasone dipropionate (Beclovent, Vanceril) | bronchial asthma- long term tx |
| Bechlomethasone dipropionate (Beclovent, Vanceril) | cortocosteriod |
| MAST CELL STABILIZERS | Cromolyne & nedocromilprophylactic asthma |
| indomethacin (Indocin) | tx for rhematoid arthritis, osteoarthritis, acute bursitis or tendinits, ankylosing spondylitis, and acute gouty arthritis. |
| indomethacin (Indocin) | tx for rhematoid arthritis, osteoarthritis, acute bursitis or tendinits, ankylosing spondylitis, and acute gouty arthritis. |
| aspirin | tx for inflammatory disorders,mild to moderate pain, fever, prophylaxix of TIAs and MIs |
| ibuprofen (Motrin) | blocks COX qne lipoxygenase enzymes & inhibitsprogragalndin sythesis |
| ketorolac (Toradol) | peripherally acting analgesia and antipyertic andantiinlammatory properiteis |
| ketorolac (Toradol) | short term managementof pain; not to exceed 5 days |
| celecoxib (Celebrex) | inhibits COX-2; anti-inflammatory and antipyeritc |
| celecoxib (Celebrex) | tx for osteoarthritis; relifof signsoandsymtoms of rehematoid arthritis in adutls; reduction of thenumber or adenamotous colorectoal polyps |
| allopurinol (Zyloprim) | relief of gout- inhibits the enzyme xanthing oxidase- preventsuric acid production. |
| allopurinol (Zyloprim) | SE- agranulocytosis, aplostic anemis and exfoliative drmatitis, Stevens- Johnson sydorom and toxic epidermal necrolysis |
| azathioprine (Imuran) | immunosupressant that blocks T-cell proliferation by inhibitin purin sythisis, which inturn prevens DNA sythesis |
| azathioprine (Imuran) | tx - renal transplant- adjunt for prevention or rejection;rheumatoid arthritis; chronic ulcertiv colitis, MG, and Crohn's disease. |
| cyclosporine (Sandimmune) | immunosupressant indicated for the prevention of organ refection. |
| muromonab-CD3 (OKT3) | immunosuppressant indicated forreveral of graft rejection |
| beta adrenergic agonists | used druing the acute phase of an asthmatic attack to quickly reduce airway constriction andresore airlforw to normal. |
| beta adrenergic agonists | stimulators of the sympathetic nervouse system recptors. |
| beta adrenergic agonist | imitate effects of norepinephrine on those receptors |