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rsrch pharm 2
3
doxycyline | AMINOGLYCOSIDE | clindamycin (cleocin) | vancomycin (vancocin) | ANTIVIRAL AGENTS | ACYCLOVIR (ZOVIRAX) | isoniazid |
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Tetracycline antibiotic | "BIG GUNs" bacteriocidal antibiotics with poor oral absorption | antibiotic (other class) | unlike any other antibiotic in that it binds to cell wall | agent that needs to attack in DNA or RNA | reduce viral shedding, creasee local symptomss, and cecrease severity and duration of illness. | CI inthose with optic neuritis, and thos w/ previous isoniazid associated hapteic injusry or acute liver disease. |
Bacteriostatic: Inhibits protein synthesis of susceptible bacteria, causing cell death | capable of toxicity to renal and ears | indicated for strains of anaerobes, streptococci, staphylococci, pneumococci | used for MRSA bacterias; antibiotic of choice for antibiotic induced psuedomembranous colitis | used for HSV 1 & 2 and VZV, which causes chiken pox and shingles | metabolized through liver: therefore cannot be taken if liver does not have enough enzymes | |
Oral tetracyclines used for acne, uncomplicated adult urethral, endocervical, or rectal infections caused by C. tracho | gentamycin, amikacin | inihibits protien sythesis in bacteria by binding to S50 ribosomal subunit | destroys bacteria by binding to wall and inhibits growth of cell wall. | acyclovir | antiviral | antitubucular |
Dental: Discoloring and inadequate calcification of primary teeth of fetus if used by pregnant women, discoloring and inadequate calcification of permanent teeth if used during period of dental development | BUN and creatinine levels measured aand during aminoglycoside therapy | Adult IV/PO- 300-900; mg. bid | not active against gram negative bacteria | (blank) | (blank) | (blank) |
(blank) | SE- symptoms of ototoxicity; tinnitus; dizziness,feeling of fullness in ears, hearing loss | (blank) | (blank) | (blank) | (blank) | (blank) |
(blank) | PEAK and TROUGH blood levels one hour before and after drug admin | (blank) | (blank) | (blank) | (blank) | (blank) |