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Platinum Analogs
Important fun facts about the platinum analogs
Question | Answer |
---|---|
How was cisplatin discovered? | when used in as an electrode study, evaluating electricity's effect on cancer cells |
What is the cumulative dose limiting toxicity of cisplatin? | Renal toxicity |
What is the cumulative dose limiting toxicity of oxaliplatin? | neurotoxicity |
How is carboplatin dosed? | Calvert formula |
What toxicity guides carboplatin dosing | Thrombocytopenia |
What platinum analog has the highest emetogenic potential? | Cisplatin |
What best describes the class/MOA of platinum analogs? | non-traditional alkylating agents |