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1. Cephalosporins & penicillin bactericidal and work be interfering with bacterial cell wall synthesis.
2. Toxic effects of aminoglycoside ototoxicity (hearing loss, tinnitus, and dizziness), nephrotoxicity (decrease urination, proteinuria, increased BUN, and serum creatinine) and interaction is with Lasix.
3. Side effects of most antibiotics drug allergies, fever, rash, GI tract and most common interactions are antacids, Lasix, milk, cheese, and iron.
4. Penicillin don’t take with caffeine, citrus, colas, and juices.
Cephalosporins take with food to decrease GI upset
Sulfonamides take with food and lots of fluids.
Tetracyclines not take with dairy products, antacids, or iron
Quinolones limit dairy, antacids, peanuts, veg oils, and Na bicarbs and increase fluids
Vancomycin increase fluids to 2000 ml to prevent nephrotoxicity
5. Tetracyclines not for children under 8 or pregnant women and can cause tooth enamal to turn grey.
6. Macrolides and ketolides (erythromycin and Zithromax) are for respiratory infections and are short doses.
7. Vancomycin (Vancocin) is the antibiotic for MRSA.
8. The most common side effect of acyclovir (Zovirax) transient burning when applied topically.
9. Fuzeon an HIV drug that is classed as a fusion inhibitor
10. Zidovudine (AZT, Retrovir) has dose-limiting bone marrow suppression.
11. Didanosine (Videx) do not suppress bone marrow and will be used alternate to AZT.
12. Indinavir (Crixivan) increases CD4 count.
13. Non-retroviral: acyclovir used to treat herpes simplex virus,
oseltamivir used to treat the flu, zanamivir is used to treat the flu in inhaled med and both drugs should be taken within 2 days of symptoms.
14. Retroviral: zidovudine used to treat patient with HIV who have AIDS
didanosine used to treat HIV patients and is not a bone marrow suppressing drug.
15. Most common TB meds INH, do not take with antacids and use a oral contraceptive. Pyridoxine (vitamin B6) is given to prevent INH-precipitated peripheral neuropathies and avoid numbness and tingling in the extremities. It also can cause liver toxicity.
tb Treatment also may last 12-24 months “Rifa” drugs turns feces red and can stain clothes.
18. Amphotericin B (Amphocin, Fungizone) is used to treat yeast infections and severe systemic mycoses. The adverse effects are fever, chills, hypotension, tachycardia, malaise, anorexia, and N/V. Pretreat with antipyretics, antihistamines, and antiemetics.
19. Mebendazole (Vermox used to treat roundworms and some types of tapeworm infections. Diarrhea and anorexia during treatment are expected. Wear gloves when handling linens and clothing
20. Antiseptics applied to living tissues to inhibit growth
disinfectants applied to nonliving objects to kill organisms.
21. NSAIDS not used for patient with bleeding disorders, GI problems, or children under 12 due to Reye Syndrome. Cytotec prevents GI bleeding when taken with NSAIDS.
22. Allopurinol (Zyloprim) used for gout.
23. Aurothioglucose (solganol) and gold sodium tiomalate (myochrysine) used for gold treatment in patients with arthritis, IM z-track and rotate sites.
25. Azathioprine (Imuran) an immunosuppressant drug and its side effect is leukopenia it is used for rejection of kidney transplant. Labs that are used are Hgb, Hct, WBC, and platelet counts.
Created by: kcorkinsnctc
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