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Drug profiles
decadron, solumedrol, albuterol, sodium bicarb, etomidate
| Question | Answer |
|---|---|
| Sodium Bicarb GENERIC NAME | None |
| Sodium Bicarb BRAND NAME | Sodium Bicarbonate 8.4% |
| Sodium Bicarb CLASS | Buffer |
| Sodium Bicarb MECHANISM OF ACTION | Counteracts existing acidosis |
| Sodium Bicarb INDICATIONS | Acidosis, drug intoxications (barbiturates, salicylates, methyl alcohol) |
| Sodium Bicarb CONTRAINDICATIONS | Alkalosis |
| Sodium Bicarb ADVERSE REACTIONS | Metabolic alkalosis, Hypernatremia, Peripheral edema, Sodium and fluid retention |
| Sodium Bicarb NOTES ON ADMINISTRATION | none |
| Sodium Bicarb INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible with other drug infusions. |
| Sodium Bicarb DOSE/ROUTE Adult Dosage Metabolic Acidosis Cardiac arrest | 1 mEq/kg, may repeat at 0.5 mEq/kg in 10 minutes |
| Sodium Bicarb Pediatric Dosage | 1 mEq/kg IV or IO NS Can contribute to acidosis and cause fluid overload |
| Sodium Bicarb ONSET OF ACTION | Seconds |
| Sodium Bicarb PEAK EFFECTS | 1-2 minutes |
| Sodium Bicarb DURATION OF ACTION | 10 minutes |
| Sodium Bicarb AZ DRUG BOX SUPPLY RANGE | 100 mEq |
| Albuterol GENERIC NAME | Albuterol |
| Albuterol BRAND NAME | Proventil, ventolin |
| Albuterol CLASS | Sympathomimetic, bronchodilator |
| Albuterol MECHANISM OF ACTION | Binds and stimulates Beta2 receptors, resulting in relaxation of bronchial smooth muscle |
| Albuterol INDICATIONS | COPD, Asthma, bronchitis |
| Albuterol CONTRAINDICATIONS | Angioedema, sensitivity to Albuterol or levalbuterol |
| Albuterol ADVERSE REACTIONS | tremors, dizziness, tachycardia, palpitations, N/V , hyperglycemia, Hypokalemia, HA, and paradoxical bronchospasm. |
| Albuterol NOTES ON ADMINISTRATION | Pregnancy safety category C. antagonized by beta blockers |
| Albuterol INCOMPATABILITIES/DRUG INTERACTIONS | Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic. May potentiate Hypokalemia caused by diuretics. |
| Albuterol DOSE/ROUTE Adult | 2.5mg. every 20 minutes up to 3 doses. |
| Albuterol DOSE/ROUTE Pediatric >12 years | 0.5mg/kg/hr |
| Albuterol DOSE/ROUTE Pediatric <12 years | 0.15mg/kg every 20min up to 3 doses |
| Albuterol ONSET OF ACTION | 5-15min. |
| Albuterol PEAK EFFECTS | 30min-2hours |
| Albuterol DURATION OF ACTION | 3-4 hours. |
| Albuterol AZ DRUG BOX SUPPLY RANGE | 10mg |
| Decadron GENERIC NAME | Dexamethasone |
| Decadron BRAND NAME | Decadron |
| Decadron CLASS | Corticosteroid |
| Decadron MECHANISM OF ACTION | Reduces inflammation and Immune responses. |
| Decadron INDICATIONS | Anaphylaxis, spinal cord injury, asthma, croup, nonresponsive forms of shock |
| Decadron CONTRAINDICATIONS | Hypersensitivity |
| Decadron ADVERSE REACTIONS | HTN, Hyperglycemia, edema, N/V, Immunosuppresion |
| Decadron NOTES ON ADMINISTRATION | Protect from heat |
| Decadron INCOMPATABILITIES/DRUG INTERACTIONS | Calcium, Metaraminol. |
| Decadron DOSE/ROUTE Adult | 1-6mg/kg slow IV bolus |
| Decadron DOSE/ROUTE Pediatric | 0.25-1mg/kg/dose IV, IO, IM |
| Decadron ONSET OF ACTION | Hours |
| Decadron PEAK EFFECTS | 8-12 hours |
| Decadron DURATION OF ACTION | 72 hours. |
| Decadron AZ DRUG BOX SUPPLY RANGE | 8mg optional |
| ETOMIDATE GENERIC NAME | ETOMIDATE |
| ETOMIDATE BRAND NAME | Amidate |
| ETOMIDATE CLASS | Sedative/hypnotic agent |
| ETOMIDATE MECHANISM OF ACTION | Produces hypnosis rapidly causing CNS depression and anesthesia No analgesic effect |
| ETOMIDATE INDICATIONS | Induction of anesthesia for rapid sequence intubation (RSI) |
| ETOMIDATE CONTRAINDICATIONS | Hypersensitivity |
| ETOMIDATE ADVERSE REACTIONS | Hypotension, HTN, Hypoventilation, Hyperventilation, Arrhythmias, respiratory depression, temporary involuntary muscle movement, N/V |
| ETOMIDATE NOTES ON ADMINISTRATION | none |
| ETOMIDATE INCOMPATABILITIES/DRUG INTERACTIONS | none |
| ETOMIDATE DOSE/ROUTE ADULT | 0.3 mg/kg IV over 30-60 seconds |
| ETOMIDATE DOSE/ROUTE Peds | >10 years. Same as adult. |
| ETOMIDATE ONSET OF ACTION | 1 minute |
| ETOMIDATE PEAK EFFECTS | n/a |
| ETOMIDATE DURATION OF ACTION | 3-5 minutes |
| ETOMIDATE AZ DRUG BOX SUPPLY RANGE | 80mg |
| Solu-Medrol GENERIC NAME | Methylprednisolone |
| Solu-Medrol BRAND NAME | Solu-Medrol |
| Solu-Medrol CLASS | Anti-inflammatory Glucocorticoid |
| Solu-Medrol MECHANISM OF ACTION | Reduces inflammation by multiple mechanisms. |
| Solu-Medrol INDICATIONS | Acute spinal cord trauma, anaphylaxis, Asthma, COPD |
| Solu-Medrol CONTRAINDICATIONS | fungal infections, Cushing’s syndrome, measles, |
| Solu-Medrol ADVERSE REACTIONS | HA, HTN, Sodium and water retention, CHF, Hypokalemia, N/V |
| Solu-Medrol NOTES ON ADMINISTRATION | Pregnancy safety not established, crosses the placenta and may cause fetal harm. Not effective if spinal cord injury is greater then 8 hours. |
| Solu-Medrol INCOMPATABILITIES/DRUG INTERACTIONS | Hypoglycemic responses to insulin and hypoglycemic agents may be blunted. Potassium-depleting agents may exacerbate hypokalemic effects. |
| Solu-Medrol DOSE/ROUTE Adult, Acute spinal cord injury | 30mg/kg IV over 30 minutes followed by an infusion. |
| Solu-Medrol Dose/route Adult asthma and COPD | 1-2mg/kg IV. |
| Solu-Medrol Dose/route Pediatric | Same as adult |
| Solu-Medrol ONSET OF ACTION | 1-2 hours |
| Solu-Medrol PEAK EFFECTS | Variable |
| Solu-Medrol DURATION OF ACTION | 8-24 hours |
| Solu-Medrol AZ DRUG BOX SUPPLY RANGE | 250mg |
Created by:
klindley
on 2009-06-16