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Vasopressin
| Question | Answer |
|---|---|
| Vasopressin GENERIC NAME | Vasopressin |
| Vasopressin BRAND NAME | Pitressin synthetic |
| Vasopressin CLASS | Antidiuretic hormone |
| Vasopressin MECHANISM OF ACTION | Stimulation of V1 smooth muscle receptors, potent vasoconstrictor when given in high doses. |
| Vasopressin INDICATIONS | Alternate vasopressor to the first or second dose of epinephrine in cardiac arrest, may be useful in cases of vasodilatory shock (i.e. septic shock) |
| Vasopressin CONTRAINDICATIONS | Responsive patients with coronary artery disease. |
| Vasopressin ADVERSE REACTIONS | Bronchoconstriction, ischemic chest pain, N/V, abdominal pain. |
| Vasopressin NOTES ON ADMINISTRATION | Pregnancy category C. May increase peripheral vascular resistance and provoke cardiac ischemia and angina. |
| Vasopressin INCOMPATABILITIES/DRUG INTERACTIONS | None |
| Vasopressin DOSE/ROUTE Adult | : 40 unit one time dose IV/IO to replace the first or second dose of epinephrine in cardiac arrest |
| Vasopressin ONSET OF ACTION | Immediate |
| Vasopressin PEAK EFFECTS | Variable |
| Vasopressin DURATION OF ACTION | Variable |
| Vasopressin AZ DRUG BOX SUPPLY RANGE | 40 units (optional) |