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Pharm Test 2 Jeopard
Pharmacology test 2 jeopardy questions lilk8tob
| Question | Answer |
|---|---|
| The most common adverse (allergic) reaction to penicillin | Urticaria (hives), pruritis (itching), angioedema (swollen lips) |
| Gram stain hue of bacteria most commonly destroyed by penicillins | Gram positive |
| Enzyme created by bacteria capable of destroying penicillins. | Betalactamase |
| Key drug- 3rd generation cephalosporin | Cefoxitin, ceftazidime |
| Types of organisms killed by 3rd generation cephalosporins | Best: G- poor: G+ |
| Coadministration with these may decrease oral absorption of tetracyclines | milk, antacids, iron salts |
| This reason precludes use of tetracycline in pregnant/lactating women and ped. patients | binds to calcium, stains teeth of neonate or child |
| Sulfonamides are primarily used to treat this kind of infection | UTI (high concentration in kidneys) |
| Common allergic reaction with sulfonamides | Delayed cutaneous reactions |
| Sulfonamides produce varying interaction when taken with this drug class | oral anticoagulants |
| Key drug- macrolide and common side effect | Erythromycin, stomach irritation, GI upset |
| Primary excretion site of quinolones | kidneys |
| Unless contraindicated fluid intake (ml/d) encouraged for someone on quinolones: | 3 L/day |
| Reason quinolones contraindicated in pregnant and ped. patients | shown to affect cartilage development in lab animals |
| 2 drugs or drug classes that interact with quinolones | theophylline and oral anticoagulants |
| key drug- aminoglycocides | Gentamycin, amikacin |
| Two serious toxicities of aminoglycosides | Nephrotoxicity (renal failure) and ototoxicity (hearing loss) |
| Renal function blood tests that will be monitored before and during aminoglycoside therapy | BUN and serum creatinine levels |
| Symptoms of ototoxicity | Tinnitus, dizziness, feeling of fullness in ears, hearing loss |
| Terms for blood levels drawn 1 hr after drug administration and just prior to next dose | peak and trough |
| Two drugs in "other or misc." antibiotic class | Vancomycin, Clindamycin |
| Antibiotic of choice for the treatment of MRSA | Vancomycin |
| Correct rate of IV administration of vancmycin | Over at least 60 minutes |
| Symptoms and treatment of Redman's Syndrome | hypotension, flushing of neck and face; antihistamine will be ordered |
| Two similarities of toxicity between aminoglycocides and vancomycin | nephrotoxicity and ototoxicity |