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Pharm Test 2 Jeopard

Pharmacology test 2 jeopardy questions lilk8tob

QuestionAnswer
The most common adverse (allergic) reaction to penicillin Urticaria (hives), pruritis (itching), angioedema (swollen lips)
Gram stain hue of bacteria most commonly destroyed by penicillins Gram positive
Enzyme created by bacteria capable of destroying penicillins. Betalactamase
Key drug- 3rd generation cephalosporin Cefoxitin, ceftazidime
Types of organisms killed by 3rd generation cephalosporins Best: G- poor: G+
Coadministration with these may decrease oral absorption of tetracyclines milk, antacids, iron salts
This reason precludes use of tetracycline in pregnant/lactating women and ped. patients binds to calcium, stains teeth of neonate or child
Sulfonamides are primarily used to treat this kind of infection UTI (high concentration in kidneys)
Common allergic reaction with sulfonamides Delayed cutaneous reactions
Sulfonamides produce varying interaction when taken with this drug class oral anticoagulants
Key drug- macrolide and common side effect Erythromycin, stomach irritation, GI upset
Primary excretion site of quinolones kidneys
Unless contraindicated fluid intake (ml/d) encouraged for someone on quinolones: 3 L/day
Reason quinolones contraindicated in pregnant and ped. patients shown to affect cartilage development in lab animals
2 drugs or drug classes that interact with quinolones theophylline and oral anticoagulants
key drug- aminoglycocides Gentamycin, amikacin
Two serious toxicities of aminoglycosides Nephrotoxicity (renal failure) and ototoxicity (hearing loss)
Renal function blood tests that will be monitored before and during aminoglycoside therapy BUN and serum creatinine levels
Symptoms of ototoxicity Tinnitus, dizziness, feeling of fullness in ears, hearing loss
Terms for blood levels drawn 1 hr after drug administration and just prior to next dose peak and trough
Two drugs in "other or misc." antibiotic class Vancomycin, Clindamycin
Antibiotic of choice for the treatment of MRSA Vancomycin
Correct rate of IV administration of vancmycin Over at least 60 minutes
Symptoms and treatment of Redman's Syndrome hypotension, flushing of neck and face; antihistamine will be ordered
Two similarities of toxicity between aminoglycocides and vancomycin nephrotoxicity and ototoxicity
Created by: lilk8tob
 

 



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