Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Type 2 DM Treatment

Class & GenericDosingMOAEfficacy & TargetADRsClinical Pearls
DPP-4 inhibitors: sitagliptan saxagliptan linagliptan alogliptin Daily Inhibits GLP-1 breakdown <1 Postprandial HA Nasopharyngitis Peripheral edema Pancreatitis Take w/ or w/out food High cost C/I: Hx of pancreatitis
SGLT-2 inhibitors: canagliflozin dapagliflozin empagliflozin Daily Increase urinary Glu excretion by blocking reabsorption in proximal convoluted tubule <1 Genital mycotic infections UTIs Hypotension Bone Fractures Increases urination Expensive C/I: severe renal impairment
GLP-1 agonists: exenatide liraglutide albiglutide dulaglutide Weekly-BID Increase insulin secretion; Decrease glucogon secretion; Reduce gastric emptying; Promote satiety <1 Postprandial GI Pancreatitis Medullary thyroid tumors Injectable Expensive Liraglutide indicated for weight loss C/I: Hx of pancreatitis, renal inpairment
Amylin analog: pramlintide TID Decrease glucagon secretion; Slow gastric emptying; Promote satiety <1 Postprandial GI HA Hypoglycemia Administered w/insulin (injectable) Expensive Weight loss C/I: hypoglycemia unawareness, gastroparesis
Bile Acid Binding Resin: colesevelam Daily-BID Unclear; Reduce hepatic gluconeogenesis or intestinal Glu absorption <1 Postprandial GI Expensive C/I: bowel obstruction, TGs >500
Dopamine agonist: bromocriptine Daily Unclear: Affect circadian activities the reduce caloric intake and storage <1 Fasting GI HA DZ Can decrease antipsychotic effectiveness Expensive C/I: syncopal migraine, breastfeeding, uncontrolled HTM
Biguanide: metformin Daily-BID Decrease hepatic Glu production; Decrease intestinal Glu absorption; Increase insulin sensitivity >1 Fasting GI Lactic acidosis (BBW) B12 deficiency Take w/food for GI Hold 48 hrs for contrast C/I: GFR <30, metabolic acidosis, HF
Sulfonylureas: glyburide glipizide glimepiride Daily-BID Increase insulin secretion >1 Fasting & postprandial Hypoglycemia Weight gain Skip dose if meal is skipped C/I: hypoglycemia unawareness, renal dysfunction, T1DM Glipizide for renal dysfunction
Meglitinides: repaglinide nateglinide TID Increase insulin secretion ~1 Postprandial Hypoglycemia Weight gain URTIs Skip dose if meal is skipped C/I: repaglinide + gemfibrozil, T1DM
TZDs: pioglitazone rosiglitazone Daily Increase insulin sensitivity >1 Fasting & postprandial Fluid retention Weight gain Increase lipids Fracture risk Bladder cancer (pioglitazone) Slow onset C/I: Class III/IV HF, LFTs >3x ULN
alpha-Glucosidase inhibitors: acarbose miglitol TID Slows intestinal carb digestion/absorption <1 Postprandial GI Take w/1st bite of food Use Glu to treat hypoglycemia C/I: IBD, colonic ulcerations, intestinal obstructions, cirrhosis (acarbose)
Created by: kcapizzi
Popular Pharmacology sets
top 200 drugs
top 200 drugs for 2009 with classification, route, and use
# 1 Pikes PeakCC 1st50 Top 200 drug
Sig Code Help
Common drug suffixes
conversions
top 200 drugs for a pharmacy tech exam
A set of Top 200, generic, brand, classification, drug form and stability
www.pharmteacher.com 2010 Top 200 (brand, generic, & drug class)
Laws for PTCB exam
# 1 Pikes PeakCC 2nd50 Top 200 drug
# 1 Pikes PeakCC 4th50 Top 200 drug

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards