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SNS Drugs
Adrenergic and Antiadrenergic Drugs
Question | Answer |
---|---|
Adrenergic Drugs | Action: Binds with alpha and beta receptors; Uses: Anaphylaxis, hypotension, nasal congestion, bronchoconstriction |
Alpha: Levophed | Action: vasoconstriction Features: Strong peripheral vasoconstrictor; give for low BP |
Beta: Proventil | Action: Interacts more with beta-2 receptors Features: Bronchodilation and less cardiac stimulation |
Alpha-Beta: Adrenalin | Action: Interacts with alpha and beta but more with beta-1 Features: cardiac stimulation; bronchoconstriction; general vasoconstriction at higher doses |
Antiadrenergic Drugs | Action: Blocks adrenergic receptors and interferes with NT production Uses: Peripheral vasodilation; cardiac depression; bronchoconstriction; GI/bladder relaxation |
Non-Selective Alpha Blocker: Regitine | Action: Blocks alpha 1 and 2 Features: Used to treat tissue necrosis caused by infiltration of vasoconstricting drugs |
Selective alpha-1 blocker: Minipres | Action: Blocks alpha-1 receptor and prevents SNS response in heart, blood vessels, and GI/urinary systems Features: First dose syncope; administer HS |
Selective Alpha-2 blocker: Catapres | Action: Inhibits release of norepi Features: Used for tachycardia, water and Na retention, rebound hypertension; may require diuretics to prevent enematic effects |
Non-selective beta 1,2 blocker: Inderal | Actions: Blocks cardiac stimulation and bronchodilation Features: Can cause bradycardia and increased glucose levels; do not give to diabetics or ahsmatics |
Selective beta-1 blocker: Tenormin | Action: Blocks cardiac stimulation by preventing renin release Feature: Decreases blood glucose and less bronchoconstriction |
Alpha-beta blocker: Trandate | Uses: Prevents vasoconstriction and bronchodilation; impedes glucose production; relaxes GI and bladder Feature: Orthostatic hypotension |