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GI System Disorders


Acute Gastritis transient irritation caused by local irritants and H. pylori
Chronic Gastritis A progressive disease causing thinning and degeneration of the stomach wall. Affects the parietal and chief cells: leads to decrease HCl and intrinsic factors. Seen in elderly , ETOH abusers, smokers, autoimmune etiology
Peptic Ulcer Disease A break in the mucosal lining of the lower esophagus, stomach, or upper SI; exposes the submucosal areas to gastric scretions and autodigestion
Duodenal Ulcers H. Pylori infection with hypersecretion of acid
Gastric Ulcers increased permeability to hydrogen ions
complications of PUD hemorrhage, obstruction, perforation
Ulcerative Colitis inflammatory disease of the colon
Chron's Disease inflammatory disease of the small or large intestine
Malabsorption Syndrome complication of GI disorder where nutrients are not digested and absorbed. Person experiences steatorrhea, weight loss, fatigue etc.
Dumping Syndrome Occurs after gastric bypass surgery; food rapidly enters the jejunum w/o mixing or digestion from the duodenum
Cirrhosis irreversible inflammatory disease; liver parenchymal cells are destroyed and replaced by fibrotic tissue
Postnecrotic Cirrhosis caused by viral hepatitis, drugs or toxins, or after an autoimmune disorder
Biliary Cirrhosis an obstruction of the bile ducts; possible autoimmune disorder
Portal Cirrhosis due to toxic effects of ETOH
Hepatitis A transmitted via fecal-oral route, doesn't lead to chronic hepatitis, doesn't create carrier state, occasionally causes liver failure, and a vaccine is available
Hepatitis B transmitted through contaminated blood and body fluids, may lead to liver failure and carrier state, a vaccine is available
Hepatitis C transmitted via blood and body fluids, some may become jaundiced, may lead to chronic hepatitis, carrier states, and liver cancer, no vaccine available yet
Hepatitis D transmitted via blood and body fluids; however depends on HBV infection, may lead to fulminant or chronic hepatitis
Hepatitis E transmitted via fecal-oral route and is similar to HAV, does not cause chronis hepatitis or a carrier state, occurs in developing countries
Hepatitis F&G recently discovered viruses, etiology unknown
Created by: rsg175 on 2003-12-06

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