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DU PA Fung/Vir Skin
Duke PA Fungal and Viral Infections of the Skin
Question | Answer |
---|---|
unique group of fungis that infect keratinized epithelium including hair and nails | dermatophytic infections |
three genera of fungi responsible for dermatophytic infections | microsporum, trichophyton, and epidermophyton |
aka ringworm | dermatophytic infections |
dermatophytic infection of the feet characterized by erythema, scaling, vesicles and maceration | tinea pedis |
tinea pedis is more common in __ | males |
erythema, scale and papules on heels, soles and lateral borders of foot | moccasin tinea pedis |
topical treatment for tinea pedis | must use for 2-4 weeks, imidazoles, allylamines |
oral treatment for tinea pedis | use for 2-6 weeks for severe/refractory cases imidazoles, allylamines (must monitor liver function) |
non-pharmacologic treatment for tinea pedis | air |
aka jock itch | tinea cruris |
sub-acute or chronic infection of the groin/medial thighs | tinea cruris |
differential for tinea cruris | candidiasis, erythrasma |
subacute infection of neck, trunk, and or extremities-lesions vary in size but are plaques with sharp borders, smaller pustules or vesicles may appear within the borders. central clearing is common | tinea corporis |
candida is less likely to spare the __ | scrotum |
infection of the scalp, most common in children, especially ages 6-10 years, rare in adults, often asymptomatic | tinea capitus |
tinea capitus must be treated __ | systemically |
what may be used to treat tinea capitus | griseofulvin, imidazoles or Lamisil |
infection involving sites where maceration and occlusion create a warm, moist environment. | intertriginous candidiasis |
predisposing factors for intertriginous candidiasis | obesity, diabetes, hyperhydrosis, steroid use |
treatment of intertriginous candidiasis | nystatin, imidazoles, glucocorticoids used sparingly to calm the inflammatory response |
intertriginous candidiases | large body folds (under breasts, ab folds, axillea, groin-worsened by tight/abrasive clothing/poor hygiene) small body folds (web spaces of fingers and toes, angles of mouth) |
intertriginous candidiasis of angles of mouth | angular cheilitis |
chronic, often asymptomatic, scaling superficial skin infection. Etiologic agent malasezzia furfur found as normal skin flora in persons >15yrs especially in skin sites with high sebaceous activity | tinea (Pityriasis) versicolor |
places where you don't want to put topical steroids | face, groin, axilla |
multiple well-demarcated hyper or hypo pigmented macules with fine scaling, common sites are upper trunk, axilae, groin, thighs. | tinea (Pityriasis) versicolor |
examination of this scale under microscope reveals yeast and pseudohyphae (spaghetti and meatballs) | tinea (Pityriasis) versicolor |
application of oils/grease on the face, neck and scalp will facilitate the development of | tinea (Pityriasis) versicolor |
topical treatment of tinea versicolor | selenium sulfide 2.5% daily x7 days then weekly |
oral treatment of tinea versicolor | ketoconazole (can use single does therapy), fluconazole, itraconazole |
etiologic agents of subcutaneous fungal infections (saphrophytes found in soil, vegetation especially in warm tropical climates) | sporothrix, exophila, fonsecaea, madurella, pseudallescheria |
generalized skin eruptions secondary to systemic infection-common in children, adolescents | viral exanthems |
most common viral exanthems in childhood | rubeola (measles), rubella (german measles), varicella (chicken pox), roseola, erythema infectiousum (fifth disease) |
type of exanthem characterized by generalized erythema, worse in body creases | scarlatiniform |
type of exanthem that is maculopapular | morbiliform |
type of exanthem that is characterized initially by vesicles, may evolve to papules->pustules->erosions | vesicular |
Common systemic viral illness characterized by oral lesions (erosions) and vesicular exanthem limited to distal extremities | hand foot mouth disease |
etiologic agent of hand-foot and mouth disease | coxsackie virus |
hand foot and mouth disease has epidemic outbreaks every __ years | 3 |
aka cold sores, fever blisters | herpes labialis |
treatment for herpes labilalis | penciclovir (topical), acyclovir, valacyclovir |
manifestation of herpes simplex often seen in health care professionals, especially dentists. also in daycare providers, lesions can be exquisitely painful | herpetic whitlow |
viral skin infection caused by pox virus, distinct flesh colored or pearly white papules 1-2mm with umbilicated centers. very common in children and sexually active adults. Lesions will usually resolve spontaneously | molluscum contagiosum |
complication of varicella-zoster virus infection | ophthalmic, hemiplegia |
distribution of varicella zoster virus infection | single dermatone thoracic>trigeminal>lumbosacral>cervical |
treatment for varicella-zoster virus infection | high dose acyclovir, valacyclovir, famciclovir. ideally started within 72 hours of lesion eruption |
tx in patients with shingles that are greater then 50 years old offer | prednisone |
pain treatment for post herpetic neuralgia | gabapentin, pregabalin, tricyclics, topicals (capsaicin, lidocaine) |