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Pharm test 1 adrener

Pharm. Ch 17-18 by lilk8tob

DefinitionWord
drugs that stimulate the sympathetic nervous system. adrenergics
Adrenergics are also called: (2) adrenergic agonists or sympathomimetics because they mimic the effects of the sympathetic neurotransmitters norepinephrine and epinephrine
adrenergic receptors that are further divided into alpha1- and alpha2-adrenergic receptors and are differentiated by their location on nerves alpha-adrenergic receptors
Bodily functions that are involuntary and result from physiologic activity of the ANS. autonomic functions
Controls autonomic bodily functions autonomic nervous system (ANS)
Located on postsynaptic effector cells- the cells, muscles, and organs that the nerves stimulate. Beta-adrenergic receptors
Beta1-adrenergic receptors are primarily in: the heart
beta2-adrenergic receptors are located in the: smooth muscle of the bronchioles and arterioles and in visceral organs
substances that can produce a sympathomimetic response. They are either endogenous catecholamines (such as epinephrine, norepinephrine, and dopamine) or synthetic catecholamines. catecholamines
adrenergic receptors that, when stimulated by dopamine, cause the renal, mesenteric, coronary, and cerebral arteries to dilate and the flow of blood to increase dopaminergic receptors
pupillary dilation, whether natural (physiologic) or drug-induced mydriasis
topically applied eye medications ophthalmics
refers to an increased heart rate positive chronotropic effect
causes an increase in conduction through the atrioventricular node positive inotropic effect
the space between the nerve ending and the effector organ synaptic cleft
paroxysmal chest pain caused by myocardial ischemia angina
drugs that bind to adrenergic receptors and inhibit or block neurotransmitters antagonists
the characteristic of beta-blockers to inhibit stimulation of the heart by circulating catecholamines cardioprotective
beta-blocking drugs that are selective for beta1-adrenergic receptors. cardioselective beta-blockers
cardioselective beta-blockers are also called: beta1-blocking agents
irregular heartbeat dysrhythmia
leaking of fluid from the blood vessel into the tissues extravasation
the production of glucose from glycogen in the liver, which is reduced by beta-blockers glycogenolysis
action of agents within the beta-blocking class. A drug that mimics the activity of the adrenergic system intrinsic sympathomimetic activity (ISA)
attraction to lipid or fat lipophilicity
beta-blocking drugs that block both beta1- and beta2-adrenergic receptors nonselective beta-blockers
abnormally low blood pressure occuring when a person assumes the standing position orthostatic hypotension
drugs used to treat postpartum and postabortion bleeding caused by uterine relaxation and enlargement. They stimulate the smooth muscle of the uterus to contract oxytocics
vascular tumor that secretes norepinephrine and stimulates the CNS pheochromocytoma
another name for adrenergic antagonists sympatholytics
system of classifying antidysrhythmic agents Vaughan Williams classification
Albuterol (*) Ventolin
Epinephrine (*) Adrenalin
Pseudoephedrine (*) Afrin
Dobutamine (*) Dobutrex
Albuterol is a (category) selective beta2 adrenergic
Epinephrine is a (cat.) natural mixed alpha and beta
Pseudoephedrine is a (cat.) stereoisomer of ephedrine
Dobutamine is a (cat.) beta1-selective vasoactive adrenergic drug similar to natural dopamine
Albuterol effect bronchodilator
Epiniphrine effects vasoconstriction, increased BP, cardiac stimulation, dilation of bronchioles
Pseudoephedrine effect nasal decongestant
Dobutamine effect increases cardiac output by increasing contractility (positive inotropy), which increases stroke volume
metaprolol (*) Lopressor
propranolol (*) Inderal
sotalol (*) Betapace
phentolamine (cat.) alpha blocker
prazosin (cat.) alpha1-adrenergic blocker
metaprolol (cat.) beta1-blocker
propranolol (cat.) nonselective beta1 and beta2 blocker
sotalol (cat.) nonselective beta blocker
phentolamine effect reduces peripheral vascular resistance
phentolamine used to treat hypertension, pheochromocytoma, extravasation of vasopressors
prazosin effect relaxes & dilates the vasculature & smooth muscle around the prostate
prazosin uses hypertension, urinary obstruction in men w/ BPH
metaprolol uses post-MI, hypertension, early MI
propranolol uses angina, hypertension, dysrhythmias, post MI, migraine, tremor, pheochromocytoma
sotalol effect antidysrhythmic
sotalol uses difficult to treat dysrhythmias
Created by: lilk8tob on 2005-09-09



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