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PHARM Equations
WVSOM -- Pharmacology Equations
Question | Answer |
---|---|
Clearance (4) | (Cu X urine vol)/(Cp X time) OR rate of elimination/Cp OR (.7 X Vd)/t 1/2 OR infusion rate/Css |
Vd | dose/Cp |
Css | (1.44 x bioavailability x dose x t1/2)/(Vd x dosing interval) |
Loading Dose | Css x Vd |
Maintenence Dose | CL x Css x T |
new dose (with half life) | (t1/2 N / t1/2 D) x regular maintenance dose |
new dose (with clearance) | (CL d)/(CL N) x regular maintenance dose |
New interval (with half life) | (t1/2 D/t1/2 N) x interval of administration |
New interval (clearance) | (CL N / CL D) x interval of administration |
extraction ratio | (in - out)/in |
HH equation for weak acid | pH = pKa + log ([Ionized]/[Unionized]) |
HH equation for weak base | pH = pKa + log ([Unionized]/[Ionized]) |
TI | LD50/ED50 |