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Keitha's Study Guide

5th Mod Week 3

QuestionAnswer
Classes of medication that affect the immune system Days for the treatment of HIV/AIDS, TB, and Malaria.
What are antibodies(Immunoglobulins)? Proteins that specifically seek and bind to the surface of pathogens/antigens.
What are antigens? Specific molecules that trigger an immune response.
What are pathogens? A disease causing organisms.
List the 4 basic types of microorganisms. Bacteria, viruses, fungi, and parasites
What does each one do? Bacteria: single cell organisms with cell wall and cellular organells that allows them to live independtly in the environment.Viruses: tiny genetic parasites that require the host cell to replicate and spreaFungi: Nonphotosynthetic, eukoryotic single
Name the three main routes of pathogens transmission. Ingestion, Inhalation, and Physical contact.
How are sexually transmitted disease transmitted? Through physical contact.
What is the most common form of transmission of pathogens? "Unwashed Hands", the #1 method for preventing and for PT to prevent from pathogens contaminating a drug is by washing their hands.
What is anti-infective? A general term under which various types of drugs are subclassified.
What are antibacterials? A way to treat anti-infective bacteria
What are antivirals? A way to treat anti-infective viruses
What are antifungals? A way to treat andi-infective fungi
What are anti-microbial? Another name for anti-infective and means against the growth of a microorganisms or microbe.
Major types of antibodies by Drug Class: Sulfa drugs, penicillin(PCN's), cephalosporin, aminoglycosides, Tetracycline(TCN's), Macrolides, and synthetic antibacterial agents such as ntirofurontin and the quinolones.
What do Penicillins do? They are divided into 4 groups and then again in 4 generations.
Name the peniciliins: Natural PCN's, penicillinase-resistant PCN's, aminopenicillins, and extended spectrum pcn's.
Name the allergies to PCN: Rash or GI disturbance,anaphylactic shock(epinephrine must be administered within 5-20 min. or the person may die.)
Examples of PCN: 1st generation-natural PCN-penicillin G benzathine(Bicillin)penicillinase-resistant PCN-methocillin(staphcillin)
2nd Generation-Aminopenicillins-ampicillin(Ominiphen) Extended spectrum penicillins
3rd Generation-ticarcillin(Ticar)4th Generation-piperacillin(Pipracil)
What is cephalosporins? Chencial couisin to PCN. If pts. have a reaction to PCN most likely they will have one to cephalosporins.
Name the 4 generations cephalosporins are divided into. 1st Generation-Cephalexin(keflex)2nd Generation-Cefaclor(ceclor)3rd and 4th Generation-Cefdinir(amnicef)
What are tetracyclines? TCN are used as systemic agents against acne, bacteria, protazoans, antireheumatic agents, lyme disease, and malaria.
Examples of tetracyclines: Minocyline(Minoxin)Oxytetracycline(Terramycin)
What are macrolides? mainly bacteriostatic
Examples of macrolides: Ozithromycin(Zithromax)Clarithromycin(Biaxin)
What are aminoglycosides? Potent bactericidal antibiotic and known as OTOTOXIC Drugs which can cause permanent hearing loss.
What infections do they treat? The abdomen and UT,endocarditis and bacteremia(given IV only for systemic and topically for ocular infections)
Examples of aminoglycosides: Gentamicin(garamycin)Tobramycin(Nebcin)Amikacin(Amikin)
What are florquinolones? Quinolones-are bactericidal and are used to treat severe infections of the bone and joint, skin, UT, serious ear infection, bronchitis,pneumoia, TB, inflammation of the prostate and some STD'S.
Examples of florquinolones: Ciproflaxacin(Cipro)Ofloxacin(Floxin)
What are sulfonamides? Antibiotics that contain sulfur and are used to treat UTI, bronchitis, middle ear infection, travelers diarrhea and for PCP(Pneumocytis Carini Pneumonia)-AIDS related pneumonia
Examples of sulfanmides: Sulfisoxazole(gantisin)SulfamethoxazoleTrimethoprim(Septra,bactrim)(SMZ-TMP)
How are antifungals classified? By drugs for sustematic mycosesOral drugs for mucocutaneous infectionsTopical drug for mucocutaneous infections
What is mycosis(mycoses)? A condition in which fungi pass the resistance barriers of the human or animal body and establish infections.
What is mucocutaneous zone and where do they occur? A region of skin composing both mucosa and cutaneous skin; near the oonfices of the body at which the external skin stops and the mucosa that covers the inside of the body starts.
List the major drugs for the treatment of systemic mycuses and what is it used for? Amphotencin B (Ampholin) given IVGriseofulvin(Fulvicin, Grifulvin V) given P.O.Nystatin(Mycostatin) given P.O.Fluconazole(Diflucan) given P.O. or IV; Local candida albicans(yeast infection) of the skin and mucous membrane.
Name some topical antifungal drugs: Amphotercin B (fungizone)Ciclopiox Penlac, Loprix)Clortrimazole(Lotrimin)
What are antiviral agents? Viruses that causes death and disease worldwide and have limited drugs avaiable to treat this virus.
Name the antivirals that have been successful in the U.S. that are prevented by vaccines. Measles, mumps, rubella, varicella(chicken pox), small pox and rabies.
Examples of antivirals: Aevclovirr(Zovirax)Amantadine(Symmetrol)Gancyclovir(Cylovene)
What does HAART mean? Highly Active Antiretroviral Therapy is when several antiretrovival drugs, 3 or 4, are taken in combination "HIV/AIDS Cocktail"
Created by: santhony
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