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Immuno Complement
Complement cleavage products & their activities
Question | Answer | |
---|---|---|
Opsonization of antigen | C3b & C4b | Increased phagocytosis by macrophages & neutrophils |
Chemotaxis | C3a & C5a | Attraction of neutrophils & monocytes to inflammatory site |
Degranulation | C3a & C5a (anaphylotoxins) | Release of inflammatory mediators from mast cells & basophils |
Clearance of immune complexes | C3b | Reduced buildup of potentially harmful Ag-Ab complexes |
B cell activation | C3d | Promotiono of humoral immune response |