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Powders 1
Powders 1 - DDS II
| Question | Answer |
|---|---|
| Using ___________ rather than __________ decreases the rate of solution and prevents uncontrollable effervescence. | Granules; powders |
| Benzoic acids is a(n) ______________. | Antifungal |
| Powders to be dissolved in water include: | Antacids and laxatives, Dietary/food supplement, Douche powders |
| When oxidizing agents are triturated in a mortar with a reducing agent, what may occur? | A violent explosion |
| What are prepared aggregates of powdered materials, forming larger particle (2-4 mm) called? | Granules |
| Compared to powders, what kind of flow properties do granules have? | Good flow properties? |
| What type of containers should be used for powders? | Glass or plastic containers |
| A desirable property of a powder is that it should be ___________ and should easily __________ on the surface of the skin. | Free flowing; spread |
| Why are oral antibiotics prepared in powder or granules? | For stability |
| Which will have a faster onset, a tablet or a powder? | Powder |
| What method is used to reduce the particle size of insoluble materials when compounding ointments and suspensions? | Levigation |
| Salicylate is a(n) ______________. | Keratolytic |
| A dry mixture of sodium bicarbonate, citric acid and tartaric acid is what kind of granule? | Effervescent |
| Chartule is an example of ______________. | Divided powders |
| Insufflators are used for ______________. | Delivering a stream of powder |
| Particle size of a powder has an influence on what (5 items)? | Dissolution rate; Suspendability or rate of settling; Uniform distribution; Penetrability of powders in inhalation solutions; Topical preparations |
| Powders used to clean the teeth are called ___________. | Dentifrices |
| Substances which become powdery and liberate their water of crystallization are called ______________. | Efflorescent |
| What kind of powders are intended for topical use? | Dusting powders |
| Why do powders have a faster onset of therapeutic benefit? | Disintegration is not required |
| Substances which absorb moisture from the air to the extent that they liquefy by partially or wholly forming solution are called ___________. | Deliquescent |
| The process of particle size reduction is called ____________. | Comminution |
| The most common acids used for effervescent granules are ________ (4). | Citric acid, Tartaric acid, Malic acid, Sodium dihydrogen phosphate |
| What is liberated from a mixture of sodium bicarbonate, citric acid and tartaric acid when the mixture is added to water? | Carbon dioxide |
| How can the problem of an efflorescent powder becoming pasty due to liberation of water be overcome? | By using the corresponding anhydrous salt. |
| How is an eutectic mixture recognized? | By the liquefaction of two or more substances upon admixture |
| How can the formation of an eutectic mixture be avoided when dispensing components that will form a euctectic mixture? | By taking one powder of each kind as a dose |
| How is the bioavailability of a powder enhanced? | By reducing particle size |
| How are granules prepared? | By moistening the desired powder and passing through desired sieves, then dried. |
| In what three forms can powders be prepared? | Bulk powders, divided powders, or granules |
| Antacids would be an example of a(n) ______________ (divided powder / bulk powder). | Bulk powder |
| How can oxidizing agents be mixed with reducing agents without causing a violent explosion? | Both substances should be triturated separately and then combined with other ingredients and gently mixed |
| Zinc oxide is a(n) ___________ and a(n) _________. | Astringent, adsorbent |
| An intimate mixture of dry, finely divided drugs and/or chemicals that are intended for internal or external use describes a __________. | Powder |
| A unifrom sedimentation rate if the powder is used in a suspension is an advantage of ___________. | Uniform particle size |
| Calcium carbonate is a(n) ___________ and a(n) _________. | Astringent, adsorbent |
| Camphor is a(n) _______________. | Antipruritic |
| What size sieve range are granules usually in? | 4-12 sieve size |
| Once an oral antibiotic is reconstituted, what is its shelf life? | 1-2 weeks |
| When citric acid and tartaric acid are used in combination in an effervescent granule, what ration is used? | 1:2 (citric acid:tartaric acid) |
| What are the advantages of a uniform particle size? | 1. Insures a uniform dissolution rate for dissolving; 2. Inures a uniform sedimentation rate if used in suspension; 3. Minimal stratification when powders are stored or transported. |
| What is the general range of sizes for a powder? | 0.1 to 10 micron in size |
| What are two requirements for dusting powders? | (1) Must be homogenous, and (2) must be free from potential local irritation |
| Define absorptive. | The uptake of liquid into the fibers of a substance. |
| What can happen if the particles size distribution of a powder is not uniform? | The powder can segregate according to the different particle sizes which may result in inaccurate dosing or inconsistent performance. |
| The fact that it can be administered easily to infants and young children who cannot swallow tablets or capsules is an advantage of _________. | Powders |