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Handbook Chapter 1
Question | Answer |
---|---|
Why is bacterial contamination of platelets of special concern? | because this component is stored at room temperature (20-24 degrees C) |
The most common bacteria species isolated in platelet products | coagulase negative Staphylococcus, Streptococcus species, Staphylococcus aureus and E. coli |
Volume RBCs in apheresis platelets | less than 2 ml |
Volume of RBCs in random donor platelet | 0.5 ml |
Can ABO incompatible platelets be issued? | yes |
Immune refractoriness in platelets is most commonly associated with these antibodies | antibodies to HLA antigens; rarely, with antibodies to platelet specific antigens |
What is the blood product "Thawed plasma?" | FFP or FP24 which has been thawed for 24 hours. It can be stored refrigerated for up to 4 additional days. |
The most frequent cause of transfusion related fatalities | TRALI (Transfusion related acute lung injury); TACO is #2 |
Cryoprecipitated AHF is a concentrated source of these proteins | Factor VIII, vWF, fibrinogen, fibronectin, and Factor XIII |
The main source of concentrated fibrinogen in the US for the treatment of patients with acquired deficiency | cryo |
This blood product is beneficial in bleeding tendency associated with uremia | cryo |
True or false: Cryoprecipitate must be type specific | false |
QC requirements for leukoreduced RBCs | <5 x 10(6) WBCs and must retain 85% of original RBCs |
Leukoreduction decreases the risk of these 3 things | 1. FNHTR 2. CMV 3. HLA alloimmuniztion |
does leukoreduction mitigate TRALI risk? | No |
The minimum radiation dose for a blood component is | 25Gy at center; 15 Gy at any point in the bag |
Which one does not need to be irradiated: A. RBCs B. apheresis platelets C. FFP | C. FFP ( also cryo) because acellular |
Why would you irradiate a blood product? | to prevent Graft versus host disease (GVHD) |
Washing is associated with __% loss of RBCs | 20% |
Washing is associated with __% loss of platelets | 33% |