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BB guy testing

blood donor testing

QuestionAnswer
Number one cause of fatal HTR’s clerical error
Type and screen must be repeated every___ hours following a transfusion 72 hours
Type and cross specimens are held for __ days after a transfusion 7 days
The FDA requires type and screen panels to include these antigens Antigens represented required by FDA: i) D, C, c, E, e, Fya, Fyb, Jka, Jkb, K, k, Lea, Leb, M, N, P1, S, s
What is the risk of acute hemolytic reaction? 1 in 25,000 transfusions
What is the risk of HIV-1 infection from a transfusion? 1 in 1,467,000
What is the risk of Hepatitis B infection from a transfusion? 1 in 282,000-1,000,000 (highest risk of major viruses)
What is the risk of Hepatitis C infection from a transfusion? 1 in 1,149,000
What is the risk of HTLV1/2 from a transfusion? 1 in 4,364,000
What is the risk of WNV infection from a transfusion? remote
What is the risk of syphilis from a transfusion? remote
What is the risk of HIV-2 from a transfusion? remote
What is the risk of T. cruzi from a transfusion? remote
What is the risk of bacterial infection from a transfusion? platelets: 1 in 75000; RBC: 1 in 500,000
Genetic material of Hepatitis B virus DNA virus (Hepadnavirus)
Most likely of the major viruses to be transmitted via transfusion HBV is currently the most likely of the major viruses to be transmitted via transfusion!
#1 reason for hepatic transplant in the US Hepatitis C
Genetic material of Hepatitis C virus RNA
Window period for NAT test for HCV about 7 days
Genetic material of HIV RNA
NAT window period for HIV window period 9-10 days
HTLV-I disease associations HTLV-I disease associations 1) Adult T-cell leukemia/lymphoma (ATLL) 2) HTLV-associated myelopathy (HAM; formerly called “tropical spastic paraparesis”)
HTLV-II disease associations no clear-cut disease associations
WNV symptomatic infections result in this length of deferral Confirmed/suspected WNV infection: 28 days from symptom onset or 14 days after symptoms resolved
A donor has a positive NAT test for West Nile Virus. He is asymptomatic. How long should he be deferred from blood donation? 120 days from test date
What is the vector for Chaga's disease? Transmitted through bite of reduviid bug (“kissing bug”) in Central/South America
What are the testing requirements for Chaga's disease for blood donors? one time per lifetime of donor
Strategies to reduce the risk of transfusion transmitted CMV seronegative donors and leukocyte reduced products
Parvovirus B19 causes these diseases “Fifth disease” in children, red cell aplasia in adults
Parvovirus B19 enters RBCs through this antigen P antigen
Are donors tested for babesia? in northeast and Midwest states; 14 states and D.C.
Created by: jfshikle
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